633302-56-4Relevant academic research and scientific papers
Asymmetric total synthesis of the myxobacteria metabolites crocacins A-D
Feutrill, John T.,Lilly, Michael J.,White, Jonathan M.,Rizzacasa, Mark A.
, p. 4880 - 4895 (2008/09/21)
The total syntheses of crocacins A-D are described. The key steps were a syn-aldol reaction followed by anti-reduction to secure the stereotetrad and acylation of an ene- or dienecarbamate to form the enamide. Crown Copyright
Total synthesis of (+)-crocacin A
Feutrill, John T.,Rizzacasa, Mark A.
, p. 783 - 785 (2007/10/03)
The first asymmetric total synthesis of the electron-transport inhibitor crocacin A (1) is described. The key step involved acylation of the anion derived from dienecarbamate (6) with the acid chloride (5) to afford the enamide (14). Desilylation, oxidati
