633302-87-1

Basic information

• Product Name: 5-benzyloxy-1-chloromethyl-7-[3-(2-methoxycarbonyl-1-methyl-1H-imidazol-4-ylcarbamoyl)propionylamino]-1,2-dihydrobenzo[e]indole-3-carboxylic acid tert-butyl ester
• Synonyms: 5-benzyloxy-1-chloromethyl-7-[3-(2-methoxycarbonyl-1-methyl-1H-imidazol-4-ylcarbamoyl)propionylamino]-1,2-dihydrobenzo[e]indole-3-carboxylic acid tert-butyl ester
• CAS NO: 633302-87-1
• Molecular Weight: 676.169
• Mol File: 633302-87-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-benzyloxy-1-chloromethyl-7-[3-(2-methoxycarbonyl-1-methyl-1H-imidazol-4-ylcarbamoyl)propionylamino]-1,2-dihydrobenzo[e]indole-3-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-benzyloxy-1-chloromethyl-7-[3-(2-methoxycarbonyl-1-methyl-1H-imidazol-4-ylcarbamoyl)propionylamino]-1,2-dihydrobenzo[e]indole-3-carboxylic acid tert-butyl ester(633302-87-1)
• EPA Substance Registry System: 5-benzyloxy-1-chloromethyl-7-[3-(2-methoxycarbonyl-1-methyl-1H-imidazol-4-ylcarbamoyl)propionylamino]-1,2-dihydrobenzo[e]indole-3-carboxylic acid tert-butyl ester(633302-87-1)

Safety Data

• Hazardous Substances Data: 633302-87-1(Hazardous Substances Data)

Upstream product

• 169770-25-6 1-methyl-4-nitro-1H-imidazole-2-carboxylic acid methyl ester 
• 286374-31-0 7-amino-5-benzyloxy-1-chloromethyl-1,2-dihydrobenzo[e]indole-3-carboxylic acid tert-butyl ester 
• 162085-97-4 methyl 4-amino-1-methyl-1H-imidazole-2-carboxylate 
• 439599-60-7 5-benzyloxy-7-(3-carboxypropionylamino)-1-chloromethyl-1,2-dihydrobenzo[e]indole-3-carboxylic acid tert-butyl ester 

Relevant articles and documents

Synthesis and cytotoxicity evaluation of novel C7-c7, C7-N3 and N3-N3 dimers of 1-chloromethyl-5-hydroxy-1,2-dihydro-3H-benzo[e]indole (seco-CBI) with pyrrole and imidazole polyamide conjugates.

The C7-C7, C7-N3 and N3-N3 dimers of 1-chloromethyl-5-hydroxy-1,2-dihydro-3H-benzo[e]indole (seco-CBI) with pyrrole and imidazole polyamides were synthesized and preliminary anti-cancer evaluation carried out by NCI against three types of cancer cells.