6334-01-6

Basic information

• Product Name: p-(ethylsulfonyl)-anilin
• Synonyms: 4-(ethylsulfonyl)aniline HCl;p-(ethylsulfonyl)-anilin;4-(ethylsulfonyl)aniline hydrochloride;Nsc31377;4-(Ethylsulfonyl)benzenaMine;4-(Ethanesulfonyl)aniline;[4-(Ethylsulfonyl)phenyl]amine;4-13-00-01290 (Beilstein Handbook Reference)
• CAS NO: 6334-01-6
• Molecular Formula: C₈H₁₁NO₂S
• Molecular Weight: 185.24344
• Mol File: 6334-01-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 388.6°C at 760 mmHg
• Flash Point: 188.8°C
• Appearance: /
• Density: 1.234g/cm³
• Vapor Pressure: 3.04E-06mmHg at 25°C
• Refractive Index: 1.559
• CAS DataBase Reference: p-(ethylsulfonyl)-anilin(CAS DataBase Reference)
• NIST Chemistry Reference: p-(ethylsulfonyl)-anilin(6334-01-6)
• EPA Substance Registry System: p-(ethylsulfonyl)-anilin(6334-01-6)

Safety Data

• Hazardous Substances Data: 6334-01-6(Hazardous Substances Data)

Usage

General Description

P-(ethylsulfonyl)-anilin, also known as ethylsulfamethoxine, is a chemical compound belonging to the class of sulfonamide antibacterial agents. It is used in veterinary medicine as an antibiotic to treat a wide range of bacterial infections in animals, including respiratory, urinary, and gastrointestinal infections. P-(ethylsulfonyl)-anilin works by inhibiting the growth and reproduction of bacteria, making it an effective treatment for bacterial diseases in animals. It is available in various formulations such as tablets, powders, and solutions for easy administration to different animal species. Due to its broad spectrum of activity and low toxicity, p-(ethylsulfonyl)-anilin is widely used to combat bacterial infections in livestock, poultry, and other animals.

InChI:InChI=1/C8H11NO2S/c1-2-12(10,11)8-5-3-7(9)4-6-8/h3-6H,2,9H2,1H3

Upstream product

• 121-60-8 p-acetylaminobenzenesulfonyl chloride 
• 1849-36-1 para-nitrobenzenethiol 
• 7205-80-3 1-(ethylsulfonyl)-4-chlorobenzene 
• 710-24-7 4-acetamidobenzenesulfinic acid 
• 350-46-9 4-Fluoronitrobenzene 
• 7205-60-9 1-(ethylsulfanyl)-4-nitrobenzene 
• 86810-68-6 4-(Aethylsulfonyl)acetanilid 
• 7205-81-4 1-(ethylsulfonyl)-4-nitrobenzene 

Downstream Products

• 1054579-36-0 N-(4-(ethylsulfonyl)phenyl)-6-(4-(3-isopropyl-1,2,4-oxadiazol-5-yl)piperidin-1-yl)-5-nitropyrimidin-4-amine 
• 1400220-83-8 1-(4-ethanesulfonyl-phenyl)-3-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-urea 
• 99170-05-5 N-(4-ethanesulfonyl-phenyl)-N'-methyl-thiourea 
• 1179329-53-3 1-{2-[3-(4-Cyano-3-cyclopropylphenyl)-5,5-dimethyl-2,4-dioxoimidazolidin-1-ylmethyl]-5-fluorophenyl}-3-(4-ethanesulfonylphenyl)urea 

Relevant articles and documents

Porous polymeric ligand promoted copper-catalyzed C-N coupling of (hetero)aryl chlorides under visible-light irradiation

A porous polymeric ligand (PPL) has been synthesized and complexed with copper to generate a heterogeneous catalyst (Cu@PPL) that has facilitated the efficient C-N coupling with various (hetero)aryl chlorides under mild conditions of visible-light irradiation at 80 °C (58 examples, up to 99% yields). This method could be applied to both aqueous ammonia and substituted amines, and is compatible to a variety of functional groups and heterocycles, as well as allows tandem C-N couplings with conjunctive dihalides. Furthermore, the heterogeneous characteristic of Cu@PPL has enabled a straightforward catalyst separation in multiple times of recycling with negligible catalytic efficiency loss by simple filtration, affording reaction mixtures containing less than 1 ppm of Cu residue. [Figure not available: see fulltext.]

3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

Syntheses of Some Alkyl-, Cycloalkyl-, and Aryl-(4-aminophenyl)-sulfones

Syntheses of (4-aminophenyl)-alkyl, -cycloalkyl and -aryl sulfones 2 were achieved both by alkylation of 4-(acetylamino)-benzenesulfinic acid (7) to the corresponding acetanilides 9 followed by hydrolysis and by oxidation of the appropriate (4-nitrophenyl)-sulfides 11 to (4-nitrophenyl)-sulfones 1 with subsequent Bechamp reduction.