63352-99-8 Usage
Uses
Used in Pharmaceutical Industry:
3,5-Dichlorophenylhydrazine hydrochloride is used as a synthetic intermediate for the preparation of various pharmaceutical compounds. It plays a crucial role in the synthesis of drugs with diverse therapeutic applications, including the preparation of [2-(3,5-dichlorophenyl)-1,1-dioxo-2,3-dihydro-1H-1λ6-[1,2,3,5]thiatriazol-4-yl]dimethylamine, which is a compound with potential therapeutic properties.
In the field of organic chemistry, 3,5-Dichlorophenylhydrazine hydrochloride is used as a reagent for the synthesis of various organic compounds. Its ability to form derivatives and participate in chemical reactions makes it a valuable component in the development of new chemical entities with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 63352-99-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,3,5 and 2 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 63352-99:
(7*6)+(6*3)+(5*3)+(4*5)+(3*2)+(2*9)+(1*9)=128
128 % 10 = 8
So 63352-99-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H6Cl2N2.ClH/c7-4-1-5(8)3-6(2-4)10-9;/h1-3,10H,9H2;1H
63352-99-8Relevant academic research and scientific papers
Synthesis of Aryl Hydrazines via CuI/BMPO Catalyzed Cross-Coupling of Aryl Halides with Hydrazine Hydrate in Water
Kumar, Siripuram Vijay,Ma, Dawei
supporting information, p. 1003 - 1006 (2018/09/20)
The N,N’-bis(2,6-dimethylphenyl)oxalamide was discovered as a powerful ligand for Cu-catalyzed cross-coupling of aryl halides with hydrazine hydrate, leading to the formation of a variety of aryl hydrazines at 80 oC in water under the assistance of K3PO4 and 4 mol% cetyltrimethylammonium bromide from aryl bromides and aryl iodides. Good to excellent yields were observed in most cases.
Piecing together the puzzle: Understanding a mild, metal free reduction method for the large scale synthesis of hydrazines
Browne, Duncan L.,Baxendale, Ian R.,Ley, Steven V.
supporting information; experimental part, p. 10296 - 10303 (2012/01/04)
A key intermediate for the synthesis of hydrazines via a mild, metal free reduction of diazonium salts has been isolated and characterized by X-ray analysis. The presence of this intermediate is general, as demonstrated by the preparation of a number of analogues. A discussion of the mechanism and potential benefits of such a process are also described.
