63359-84-2Relevant academic research and scientific papers
2-acetylphenol analogs as potent reversible monoamine oxidase inhibitors
Legoabe, Lesetja J.,Petzer, Anél,Petzer, Jacobus P.
, p. 3635 - 3644 (2015)
Based on a previous report that substituted 2-acetylphenols may be promising leads for the design of novel monoamine oxidase (MAO) inhibitors, a series of C5-substituted 2-acetylphenol analogs (15) and related compounds (two) were synthesized and evaluate
Synthesis of functionalized acetophenones as protein tyrosine phosphatase 1B inhibitors
Dixit, Manish,Tripathi, Brajendra K.,Srivastava, Arvind K.,Goel, Atul
, p. 3394 - 3397 (2007/10/03)
Protein tyrosine phosphatase 1B (PTP1B) is an enzyme that plays a critical role in down-regulating insulin signaling through dephosphorylation of the insulin receptor. Studies have shown that PTP1B knock-out mice showed increased insulin sensitivity in mu
