862823-92-5Relevant academic research and scientific papers
Synthesis of functionalized acetophenones as protein tyrosine phosphatase 1B inhibitors
Dixit, Manish,Tripathi, Brajendra K.,Srivastava, Arvind K.,Goel, Atul
, p. 3394 - 3397 (2007/10/03)
Protein tyrosine phosphatase 1B (PTP1B) is an enzyme that plays a critical role in down-regulating insulin signaling through dephosphorylation of the insulin receptor. Studies have shown that PTP1B knock-out mice showed increased insulin sensitivity in mu
