6336-58-9Relevant articles and documents
One-pot synthesis of substituted-amino triazole-glycosides
Sutcharitruk, Warapond,Sirion, Uthaiwan,Saeeng, Rungnapha
, (2019/09/06)
This work combined three classes of compounds in the same molecule “amino triazole-glycoside” and developed a convenient method for the synthesis of this type of compound via a one-pot two step reaction. Alkylation of amine derivatives with propargyl bromide to give propargylamine was performed in the first step subsequently followed by a ‘click’ reaction with various β-azido-glycosides in the presence of CuI in aqueous solution to provide β-amino triazole-glycosides. Thirty-two examples of glycosides were obtained in moderate to good yield using this one-pot procedure.
Synthesis, biological evaluation and molecular modeling of novel triazole-containing berberine derivatives as acetylcholinesterase and β-amyloid aggregation inhibitors
Shi, Anding,Huang, Ling,Lu, Chuanjun,He, Feng,Li, Xingshu
experimental part, p. 2298 - 2305 (2011/05/07)
A series of novel triazole-containing berberine derivatives were synthesized via the azide-alkyne cycloaddition reaction. Their biological activity as inhibitors of both acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) were evaluated. Among t
One-pot Synthesis of Secondary or Tertiary Amines from Alcohols and Amines via Alkoxyphosphonium Salts
Froyen, Paul,Juvvik, Paul
, p. 9555 - 9558 (2007/10/02)
Secondary or tertiary amines may be prepared from primary alcohols and primary or secondary amines by treating triphenylphosphine with N-bromosuccinimide (NBS) in the presence of the alcohol at low temperature, followed by addition of the amine and heating for about 1 h.The yield of amine is good to fair, decreasing sharply with sterically congested alcohols and starting amines.
