6336-72-7

Usage

InChI:InChI=1/C14H12ClNO3/c15-11-12(16-5-7-19-8-6-16)14(18)10-4-2-1-3-9(10)13(11)17/h1-4H,5-8H2

Upstream product

• 110-91-8 morpholine 
• 117-80-6 2,3-Dichloro-1,4-naphthoquinone 
• 1010-60-2 2-chloro-1,4-naphthoquinone 
• 24341-01-3 4-Deuteriomorpholine 
• 178970-82-6 4-p-chlorophenylsulfonylimino-2,2,3,3-tetrachloro-1,2,3,4-tetrahydronaphthalen-1-one 
• 139739-77-8 4-p-tolylsulfonylimino-2,2,3,3-tetrachloro-1,2,3,4-tetrahydronaphthalen-1-one 
• 137215-27-1 7-mercapto-4-methyl-2H-chromen-2-one 

Downstream Products

• 307541-95-3 2-morpholino-3-(phenylamino)naphthalene-1,4-dione 

Relevant academic research and scientific papers

Synthesis, electrochemistry, in-situ spectroelectrochemistry and molecular structures of 1,4-naphthoquinone derivatives

A novel series of 1,4-naphthoquinones substituted containing sulfur, nitrogen, oxygen atoms were synthesized. The structures of the novel products were characterized by using the various spectroscopic techniques such as 1H nuclear magnetic resonance (NMR), 13C NMR, mass spectrometry (MS), Fourier transform infrared spectroscopy (FT-IR) and microanalysis. The crystal structures of 2,3-bis(benzylsulfanyl)-1,4-napthoquinone 4 and 2,3-bis(ethylsulfanyl)-1,4-naphthoquinone 7 were determined by using X-ray single crystal diffraction method. Electrochemical behaviors of some 1,4-naphthoquinone (NQ) derivatives 3, 4, 7, 8, 9, 10, 12, 13, 15, 16, 17, 19 and 20 were studied by using cyclic voltammetry, square wave voltammetry and in-situ UV-Vis spectroelectrochemistry. The substituents of the NQ derivatives significantly altered the redox mechanism. In-situ UV-Vis spectroelectrochemical analyses of NQs supported the proposed redox mechanism.

Composition for Distructing Microalgae

The present invention relates to a composition for destroying microalgae, more specifically, to a composition for destroying microalgae containing naphthoquinone compounds having a specific exchange group. The composition for destroying microalgae, according to the present invention, can prevent green tide and red tide by being processed in areas such as cultivation facilities for microalgae, areas in which the green tide or the red tide occur, or areas expected to occur the green tide or the red tide.

NAPHTHAQUINONE METHYLTRANSFERASE INHIBITORS AND USES THEREOF

Provided herein are compounds of (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, and prodrugs thereof. Also provided are pharmaceutical compositions and methods involving the inventive compounds for the treatment of proliferative diseases (e.g., cancer (e.g., leukemia, breast cancer, melanoma, metastatic cancer) and diseases associated with inappropriate SET8 activity. Also provided are methods for inhibiting SET8 and methods for labelling SET8.

'On water' assisted synthesis and biological evaluation of nitrogen and sulfur containing hetero-1,4-naphthoquinones as potent antifungal and antibacterial agents

2-Chloro-3-(4-methylpiperazin-1-yl)naphthalene-1,4-dione (3a), 2-chloro-3-(pyrrolidin-1-yl)naphthalene-1,4-dione (3b), 2-chloro-3-(piperidin-1-yl)naphthalene-1,4-dione (3c), 2-chloro-3-morpholinonaphthalene-1,4-dione (3d), 2-chloro-3-(2-phenylhydrazinyl)n

'On water': unprecedented nucleophilic substitution and addition reactions with 1,4-quinones in aqueous suspension

Unique nucleophilic substitution and addition reactions of 1,4-quinones in aqueous suspension with aromatic amines, primary aliphatic amines, amino acid, ester of amino acid, heterocyclic amines, hydrazine, amide, and thioethers are described in absence o

Some Reactions of 4-Arylsulfonylimino-2,2,3,3-tetrachloro-1,2,3,4-tetrahydronaphthalen-1-ones

Reduction of 4-arylsulfonylimino-2,2,3,3-tetrachloro-1,2,3,4-tetrahydronaphthalen-1-ones with Zn/AcOH or Na2S2O4 results in elimination of two chlorine atoms with formation of benzoid structures.Reactions of the title compounds with dialkyl hydrogen phosp

Nucleophilic Vinylic Substitution of Halocoumarins and Halo-1,4-naphthoquinones with morpholine

Reactions of morpholine with 4-halocoumarins 1, 3-halocoumarins 3, and 2-halo-1,4-naphthoquinones 8 yield two different products, one where halogen is replaced by a nucleophile at the same carbon and the other where the nucleophile is attached to the vici