6336-72-7Relevant articles and documents
Synthesis, electrochemistry, in-situ spectroelectrochemistry and molecular structures of 1,4-naphthoquinone derivatives
Akyüz, Duygu,Deniz, Nahide Gulsah,Koca, Atif,Sayil, Cigdem
, (2021)
A novel series of 1,4-naphthoquinones substituted containing sulfur, nitrogen, oxygen atoms were synthesized. The structures of the novel products were characterized by using the various spectroscopic techniques such as 1H nuclear magnetic resonance (NMR), 13C NMR, mass spectrometry (MS), Fourier transform infrared spectroscopy (FT-IR) and microanalysis. The crystal structures of 2,3-bis(benzylsulfanyl)-1,4-napthoquinone 4 and 2,3-bis(ethylsulfanyl)-1,4-naphthoquinone 7 were determined by using X-ray single crystal diffraction method. Electrochemical behaviors of some 1,4-naphthoquinone (NQ) derivatives 3, 4, 7, 8, 9, 10, 12, 13, 15, 16, 17, 19 and 20 were studied by using cyclic voltammetry, square wave voltammetry and in-situ UV-Vis spectroelectrochemistry. The substituents of the NQ derivatives significantly altered the redox mechanism. In-situ UV-Vis spectroelectrochemical analyses of NQs supported the proposed redox mechanism.
NAPHTHAQUINONE METHYLTRANSFERASE INHIBITORS AND USES THEREOF
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Page/Page column 87; 88; 97, (2015/11/27)
Provided herein are compounds of (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, and prodrugs thereof. Also provided are pharmaceutical compositions and methods involving the inventive compounds for the treatment of proliferative diseases (e.g., cancer (e.g., leukemia, breast cancer, melanoma, metastatic cancer) and diseases associated with inappropriate SET8 activity. Also provided are methods for inhibiting SET8 and methods for labelling SET8.
'On water': unprecedented nucleophilic substitution and addition reactions with 1,4-quinones in aqueous suspension
Tandon, Vishnu K.,Maurya, Hardesh K.
experimental part, p. 5896 - 5902 (2010/01/11)
Unique nucleophilic substitution and addition reactions of 1,4-quinones in aqueous suspension with aromatic amines, primary aliphatic amines, amino acid, ester of amino acid, heterocyclic amines, hydrazine, amide, and thioethers are described in absence o