63365-21-9 Usage
Properties
1. Molecular Formula: C9H12N2O
Explanation: This formula indicates that the compound consists of 9 carbon atoms, 12 hydrogen atoms, 2 nitrogen atoms, and 1 oxygen atom.
2. Chemical Structure: Benzamide derivative with a dimethylamino group at the 5-position of the benzene ring.
Explanation: The structure features a benzene ring with an amide functional group and a dimethylamino group attached at the 5-position.
3. Usage: Commonly used in organic synthesis and pharmaceutical research.
Explanation: It serves as a building block in creating more complex organic molecules and is of interest in drug discovery due to its potential therapeutic applications.
4. Pharmacological Activities: Diverse pharmacological activities.
Explanation: The compound has shown a range of biological effects, making it valuable for research in various medical conditions.
5. Therapeutic Potential: Investigated for its potential as a therapeutic agent for cancer and neurodegenerative diseases.
Explanation: Studies are ongoing to explore its efficacy and safety in treating these specific medical conditions.
Specific Content
1. Biological Research
Explanation: It is being studied for its biological effects, including its potential role in treating cancer and neurodegenerative diseases.
2. Pharmacological Properties
Explanation: Research is focusing on understanding its pharmacological mechanisms and potential applications in drug development.
3. Current Investigations
Explanation: Ongoing studies are examining its biological and pharmacological properties to determine its suitability as a therapeutic agent.
This should give you a comprehensive overview of 2-AMINO-5-(DIMETHYLAMINO)BENZAMIDE based on the provided material.
Check Digit Verification of cas no
The CAS Registry Mumber 63365-21-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,3,6 and 5 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 63365-21:
(7*6)+(6*3)+(5*3)+(4*6)+(3*5)+(2*2)+(1*1)=119
119 % 10 = 9
So 63365-21-9 is a valid CAS Registry Number.
63365-21-9Relevant articles and documents
Copper-Catalyzed One-Pot Synthesis of Quinazolinones from 2-Nitrobenzaldehydes with Aldehydes: Application toward the Synthesis of Natural Products
Pal, Shantanu,Sahoo, Subrata
, p. 18067 - 18080 (2021/12/06)
A novel, efficient, and atom-economical approach for the construction of quinazolinones from 2-nitrobenzaldehydes has been unveiled via copper-catalyzed nitrile formation, hydrolysis, and reduction in one pot for the first time. In this reaction, urea is used as a source of nitrogen for nitrile formation, hydrazine hydrate is used for both the reduction of the nitro group and the hydrolysis of nitrile, and atmospheric oxygen is used as the sole oxidant. The method portrays a wide substrate scope with good functional group tolerances. Moreover, this method was applied for the synthesis of schizocommunin, tryptanthrin, phaitanthrin-A, phaitanthrin-B, and 8H-quinazolino[4,3-b]quinazolin-8-one.
GLUCOSE UPTAKE INHIBITORS
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Paragraph 01287; 01292-01294; 1304; 01309-01311, (2020/01/24)
this invention provides compounds that modulate glucose uptake activity and cellular transport/uptake of glucose, and particularly GLUTS3, but also including but not limited to GLUT1-14 (SLC2A1-SLC2A14). Compounds of the invention are useful for treating diseases, including cancer, autoimmune diseases and inflammation, infectious diseases, and metabolic diseases.
Molecular modelling, synthesis, cytotoxicity and anti-tumour mechanisms of 2-aryl-6-substituted quinazolinones as dual-targeted anti-cancer agents
Hour,Lee,Chen,Lee,Zhao,Lee
, p. 1574 - 1586 (2013/08/23)
Background and Purpose Our previous study demonstrated that 6-(pyrrolidin-1-yl)-2-(3-methoxyphenyl)quinazolin-4-one (HMJ38) was a potent anti-tubulin agent. Here, HMJ38 was used as a lead compound to develop more potent anti-cancer agents and to examine t
