63370-05-8

Basic information

• Product Name: Benzoic acid, 2,4,6-trimethyl-, 2-oxo-2-phenylethyl ester
• CAS NO: 63370-05-8
• Molecular Formula: C18H18O3
• Molecular Weight: 282.339
• Mol File: 63370-05-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2,4,6-trimethyl-, 2-oxo-2-phenylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2,4,6-trimethyl-, 2-oxo-2-phenylethyl ester(63370-05-8)
• EPA Substance Registry System: Benzoic acid, 2,4,6-trimethyl-, 2-oxo-2-phenylethyl ester(63370-05-8)

Safety Data

• Hazardous Substances Data: 63370-05-8(Hazardous Substances Data)

Upstream product

• 480-63-7 mesitylenecarboxylic acid 
• 70-11-1 α-bromoacetophenone 

Downstream Products

• 925461-80-9 2,4,6-trimethyl-benzoic acid (Z)-2-allyloxycarbonyloxy-2-phenyl-vinyl ester 

Relevant articles and documents

Enantioselective synthesis of α-tertiary hydroxyaldehydes by palladium-catalyzed asymmetric allylic alkylation of enolates

Chiral α-tertiary hydroxyaldehydes are very versatile building blocks in synthetic chemistry. Herein, we report the first examples of a catalytic asymmetric protocol for the synthesis of such compounds from readily available α-halo or α-hydroxy ketones or enol silyl ethers with excellent yields and enantioselectivity. Its synthetic utility is demonstrated in the short, efficient formal synthesis of (S)-oxybutynin. In this process, the chiral ligand controls the regioselectivity as well as the enantioselectivity. Copyright