6338-38-1

Usage

Chemical compound

A substance with a specific molecular structure resulting from a chemical reaction.

Complex molecular structure

The compound has a complex arrangement of atoms and bonds.

Derivative of hexitol

It is derived from a type of sugar alcohol called hexitol.

Two propanoyl groups attached

The compound has two propanoyl groups (derived from propionic acid) attached to its structure.

Used in organic chemistry

It is utilized in the field of organic chemistry for various purposes.

Building block for synthesis

It serves as a starting material for the creation of more complex molecules.

Potential applications

It has possible uses in pharmaceuticals, agrochemicals, and materials science.

Versatile reactivity

The compound can participate in a wide range of chemical reactions due to its structure.

Valuable intermediate

It is an important compound in the production of other significant molecules.

Interesting target for chemical synthesis

Its unique structure makes it a fascinating subject for chemical synthesis and research.

Research purposes

It is a valuable compound for studying various aspects of organic chemistry and molecular structure.

Upstream product

• 802294-64-0 propionic acid 
• 652-67-5 Isosorbide 
• 123-62-6 propionic acid anhydride 
• 50-70-4 D-sorbitol 

Relevant academic research and scientific papers

Preparation method of dicarboxylic acid isosorbide ester plasticizer

The invention provides a preparation method of a dicarboxylic acid isosorbide ester plasticizer. According to the method, isosorbide and monobasic acid serve as raw materials, and an esterification reaction is carried out for 0.5-48 h at the temperature of 65-250 DEG C under the catalytic effect. Dicarboxylic acid isosorbide ester is obtained through reduced pressure distillation. Dicarboxylic acid isosorbide ester is a non-toxic plasticizer, and can replace phthalic acid ester to be used for production of electric wire and cable sheaths, agricultural plastic mulching films and other polyvinyl chloride products. The product prepared through the method is high in yield, easy to separate and environmentally friendly, and has good application prospects.

Selective Esterification of 1,4:3,6-Dianhydro-D-glucitol

Esterification of 1,4:3,6-dianhydro-D-glucitol (1) with carboxylic acids in the presence of 4-dimethylaminopyridine and dicyclohexylcarbodiimide affords 2-exo-acylates 3 with high regioselectivity, in addition to small amounts of the isomeric 5-endo-acylates 4 and 2,5-diacylates 5.

Regioselective Acylation of 1,4:3,6-Dianhydro-D-glucitol

Acylation of 1,4:3,6-dianhydro-D-glucitol with anhydrides in the presence of heavy metal salts affords 5-endo-acylates with high regioselectivity, without detectable amounts of the isomeric 2-acylates.Acyl group migration occurs with preference for the 2-exo-position, on heating an acylation mixture, which contains varying amounts of 1,4:3,6-dianhydro-D-glucitol, 2- and 5-monoacylate and 2,5-diacylate, in the presence of reesterification catalysts and whilst distilling off the lower boiling 2-acylate.