6338-52-9

Usage

Uses

Used in Pesticide Production:
2-butoxyethylamine is used as a solvent in the production of pesticides, facilitating the manufacturing process and improving the effectiveness of the final product.
Used in Herbicide Production:
Similarly, in the production of herbicides, 2-butoxyethylamine acts as a solvent, enhancing the formulation and performance of these agricultural chemicals.
Used in Cleaning Products:
2-butoxyethylamine is utilized as a solvent in cleaning products, contributing to their cleaning power and effectiveness in various applications.
Used as an Intermediate in Chemical Synthesis:
In the chemical industry, 2-butoxyethylamine serves as an intermediate in the synthesis of a range of other chemicals, playing a crucial role in the production of various compounds.
Used as an Intermediate in Pharmaceutical Synthesis:
2-butoxyethylamine is also used as an intermediate in the pharmaceutical industry, aiding in the creation of different medications and contributing to the development of new drugs.

InChI:InChI=1/C6H15NO/c1-2-3-5-8-6-4-7/h2-7H2,1H3

Upstream product

• 856078-37-0 O-butyl-lactic acid amide 
• 151-56-4 ethyleneimine 
• 71-36-3 butan-1-ol 
• 56058-19-6 N-(2-butoxy-ethyl)-phthalimide 
• 111-34-2 -butyl vinyl ether 
• 6250-98-2 bis-(2-butoxy-ethyl)-amine 
• 111-76-2 2-Butoxyethanol 
• 6550-99-8 1-(2-bromoethoxy)butane 
• 162688-32-6 1-(2-Azido-ethoxy)-butane 
• 89530-91-6 butoxyacetonitrile 

Downstream Products

• 107412-46-4 (2-butoxy-ethyl)-(2,4-dichloro-benzyl)-amine 
• 162688-35-9 2-<<5-<(2-butoxyethyl)amino>pentyl>thio>-4,5-diphenyl-1H-imidazole 
• 162688-34-8 N-(2-butoxyethyl)-5-<(4,5-diphenyl-1H-imidazol-2-yl)thio>pentanamide 
• 65329-76-2 1-(2-butoxyethyl)-4-phenyl-4-imidazolin-2-one 
• 75945-76-5 1-(2-butoxyethyl)-4-phenyl-2-imidazolidone 
• 791-61-7 N-Nitroso-N-<2-butyloxy-ethyl>-p-toluolsulfonamid 

Relevant academic research and scientific papers

Direct Access to Primary Amines from Alkenes by Selective Metal-Free Hydroamination

Direct and selective synthesis of primary amines from easily available precursors is attractive yet challenging. Herein, we report the rapid synthesis of primary amines from alkenes via metal-free regioselective hydroamination at room temperature. Ammonium carbonate was used as ammonia surrogate for the first time, allowing for efficient conversion of terminal and internal alkenes into linear, α-branched, and α-tertiary primary amines under mild conditions. This method provides a straightforward and powerful approach to a wide spectrum of advanced, highly functionalized primary amines which are of particular interest in pharmaceutical chemistry and other areas.

Intermolecular Radical Mediated Anti-Markovnikov Alkene Hydroamination Using N-Hydroxyphthalimide

An intermolecular anti-Markovnikov hydroamination of alkenes has been developed using triethyl phosphite and N-hydroxyphthalimide. The process tolerates a wide range of alkenes, including vinyl ethers, silanes, and sulfides as well as electronically unbiased terminal and internal alkenes. The resultant N-alkylphthalimides can readily be transformed to the corresponding primary amines. Mechanistic probes indicate that the process is mediated via a phosphite promoted radical deoxygenation of N-hydroxyphthalimide to access phthalimidyl radicals.

Design, Synthesis, and Structure-Activity Relationship Studies for a New Imidazole Series of J774 Macrophage Specific Acyl-CoA:Cholesterol Acyltransferase (ACAT) Inhibitors

Acyl-CoA:cholesterol acyltransferase (ACAT) is the primary enzyme involved in intracellular cholesterol esterification.Arterial wall infiltration by macrophages and subsequent uncontrolled esterification of cholesterol leading to foam cell formation is believed to be an important process which leads to the development of fatty streaks.Inhibitors of the ACAT enzyme may retard this atherogenic process.We have recently discovered a series of imidazoles which are potent in vitro ACAT inhibitors in the J774 macrophage cell culture assay.This paper will describe the design, synthesis, and structure-activity relationship for this very potent series of compounds.

Catalytic process for the production of primary amines from oxyethylene glycol monoalkyl ethers

A process for the conversion of oxyethylene glycol monoalkyl ethers to the corresponding primary amines by reaction with ammonia in the presence of a nickel-copper-chromium-containing catalyst.