6338-68-7

Usage

Uses

Used in Organic Synthesis:
N,N-Dimethylethanesulphonamide is used as a solvent and reagent in organic synthesis for the preparation of pharmaceuticals and agrochemicals, facilitating various chemical reactions and improving the efficiency of the synthesis process.
Used in Plasticizer Industry:
In the plasticizer industry, N,N-Dimethylethanesulphonamide is used as a plasticizer to increase the flexibility and workability of polymers, enhancing their properties and making them suitable for a wide range of applications.
Used in Corrosion Inhibition:
N,N-Dimethylethanesulphonamide is used as a corrosion inhibitor to protect metals from corrosion, particularly in industrial settings where equipment and structures are exposed to harsh environments and corrosive substances.
Used in Polymer Processing:
In the polymer processing industry, N,N-Dimethylethanesulphonamide is used as a solvent to dissolve and process polymers, enabling the formation of films, fibers, and other polymer-based materials with specific properties and applications.

InChI:InChI=1/C4H11NO2S/c1-4-8(6,7)5(2)3/h4H2,1-3H3

Upstream product

• 124-40-3 dimethyl amine 
• 594-44-5 Ethanesulfonyl chloride 

Downstream Products

• 128622-75-3 1-<1-Hydroxy-4-t-butyl-cyclohexyl>-ethanesulfonic acid N,N-dimethylamide 
• 128622-76-4 1-<1-Hydroxy-4-t-butyl-cyclohexyl>-ethanesulfonic acid N,N-dimethylamide 
• 1222186-23-3 C₁₄H₃₀N₂O₃S₂ 
• 1222186-22-2 C₁₄H₃₀N₂O₃S₂ 

Relevant academic research and scientific papers

Highly enantioselective transfer hydrogenation of racemic α-substituted β-keto sulfonamides: Via dynamic kinetic resolution

Highly enantioselective transfer hydrogenation of β-keto sulfonamides was developed via dynamic kinetic resolution using a chiral Ru(ii) catalyst with an azeotropic solution of HCO2H/Et3N as a hydrogen donor, affording α-substituted β-hydroxyl sulfonamides in good yields with excellent diastereo- and enantioselectivities. This method is featured with mild conditions, easy operation, and a broad substrate scope, which make it possible to find wide applications in the synthesis of natural products and biologically active compounds containing the α-substituted β-hydroxyl sulfonamide core.

Secondary Reactions of Sulfenes from Sulfonyl Chlorides and Tertiary Amines. 2. Formation of Episulfones, Sulfonylsulfene - Amine S,N-Adducts and Chlorsulfines from Primary Sulfonyl Chlorides and Tertiary Amines

The reaction of primary sulfonyl chlorides 1b-m with the tertiary amine bases quinuclidine, DABCO, Me3N, Et3N, Bu3N, EtiPr2N, and 1,2,2,6,6-pentamethylpiperidine is studied in acetonitrile solution between -40 and 80 deg C.The 2,3-dialkylthiirane 1,1-dioxides 4 (trans/cis > 1) and the alkenes 5 1> are obtained in high yields with Et3N at -40 deg C.The stereochemistry is influenced by the amine base B in the ring-closure reaction and partially by epimerization of the episulfones 4.Hindered bases favor the cis, β-branched sulfonyl chlorides the trans isomer.Competing formation of the sulfonylsulfene - amine S,N-adducts 7 is only observed with quinuclidine, DABCO, and Me3N, which are also the most active amines in the epimerization of the cis-2,3-diarylthiirane 1,1-dioxides 4.Methanesulfonyl chloride (1a) yields the mesylsulfene - amine S,N-adducts 7a with Me3N and Et3N in MeCN, but thiirane 1,1-dioxide (4a) with EtiPr2N in MeCN or with Et3N in Et2O.Formation of chlorosulfines 10 is favored by higher temperature (T > 20 deg C), hindered amine bases and β-branched sulfonyl chlorides.Isolation of 10g and 10h in high yields shows that tert-alkylchlorosulfines are rather stable sulfines.