6338-89-2

Usage

Chemical structure

2-(4-chlorophenyl)-6-phenyl-4H-pyran-4-one is a chemical compound that consists of a 4H-pyran-4-one ring with a 4-chlorophenyl and a phenyl group attached to it.

Family

It belongs to the family of pyranones.

Anti-inflammatory properties

2-(4-chlorophenyl)-6-phenyl-4H-pyran-4-one has been shown to possess anti-inflammatory properties.

Antioxidant properties

The compound is also known for its antioxidant properties.

Antithrombotic properties

2-(4-chlorophenyl)-6-phenyl-4H-pyran-4-one has been shown to have antithrombotic properties.

Therapeutic applications

The compound has been studied for its potential therapeutic applications in the treatment of conditions such as ischemic heart disease, peripheral artery disease, and thrombotic disorders.

Anti-cancer properties

Cloricromene has shown potential as an anti-cancer agent and has been investigated for its effects on inhibiting tumor growth and metastasis.

Upstream product

• 107451-79-6 5-(4-chlorophenyl)-1-phenylpent-1-yne-3,5-dione 
• 143156-76-7 1-phenyl-5-p-chlorophenylpent-1-yne-3,5-dione 
• 13735-81-4 1-styrenyloxytrimethylsilane 
• 58303-62-1 5-(4-chlorophenyl)-2,3-dihydrofuran-2,3-dione 
• 58518-76-6 ((1-(4-chlorophenyl)vinyl)oxy)trimethylsilane 
• 99-91-2 para-chloroacetophenone 

Downstream Products

• 101439-41-2 2-p-chlorophenyl-6-phenyl-4H-pyran-4-thione 
• 145665-08-3 2-[5-(4-Chloro-phenyl)-5-hydroxy-4,5-dihydro-isoxazol-3-yl]-1-phenyl-ethanone oxime 
• 101576-21-0 2-(4-chloro-phenyl)-6-phenyl-pyran-4-one oxime 

Relevant academic research and scientific papers

Thermal addition reaction of aroylketene with 1-aryl-1- trimethylsilyloxyethylenes: Aromatic substituent effects of aroylketene and aryltrimethylsilyloxyethylene on their reactivity

The thermal addition reaction of various aroylketenes (C) generated by the thermolysis of 5-aryldioxofurans (A) to 1-aryl-1-trimethylsilyloxyethylenes gave 1,5-diarylpentane-1,3,5-triones (D) and 2,6-diaryl-4H-pyran-4-ones (E). The introduction of electron withdrawing substituents in the aroylketene and of electron donating substituents facilitated the addition reaction. The observed substituent effects and the reaction mechanism are interpreted in terms of molecular orbital analyses.

A New Synthesis of 3-Nitro-4H-pyran-4-ones from Acetylenic β-Diketones

A new method for the synthesis of 3-nitro-4H-pyran-4-ones is described involving nitration of acetylenic β-diketones.The 3-nitropyrones are converted into the corresponding 4-thiones which afford the respective 3-nitrooximes and N-methyl-4-thiopyridones o

Synthesis and Reactions of 3-Iodo-4H-pyran-4-ones

3-Iodo-4H-pyran-4-ones have been synthesized in excellent yield by the reaction of acetylenic β-diketones with iodine monochloride and were converted into the corresponding 4H-pyran-4-thiones.The iodopyrones and thiopyrones gave with methylamine the respe