63385-20-6

Basic information

• Product Name: Benzenecarbothioamide, N,N,3-trimethyl-
• CAS NO: 63385-20-6
• Molecular Formula: C10H13NS
• Molecular Weight: 179.286
• Mol File: 63385-20-6.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Benzenecarbothioamide, N,N,3-trimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenecarbothioamide, N,N,3-trimethyl-(63385-20-6)
• EPA Substance Registry System: Benzenecarbothioamide, N,N,3-trimethyl-(63385-20-6)

Safety Data

• Hazardous Substances Data: 63385-20-6(Hazardous Substances Data)

Upstream product

• 620-19-9 1-chloromethyl-3-methyl-benzene 
• 68-12-2 N,N-dimethyl-formamide 
• 22568-43-0 1-methyl-3-(2-nitrovinyl)benzene 
• 766-82-5 1-ethynyl-3-methyl-benzene 
• 620-23-5 m-tolyl aldehyde 
• 2947-60-6 3-methylbenzyl cyanide 
• 6935-65-5 3,N,N-trimethylbenzamide 
• 127-19-5 N,N-dimethyl acetamide 

Relevant articles and documents

Metal-free three-component synthesis of thioamides from β-nitrostyrenes, amines and elemental sulfur

A metal-free C[dbnd]C bond cleavage reaction of β-nitrostyrenes in the presence of elemental sulfur and secondary amines/amides is described. Elemental sulfur serves as both a raw material and an oxidant for C[dbnd]C bond cleavage, and secondary amines or amides are both feasible nitrogen sources. Besides mild reaction condition and simple work-up procedure, the method provided thioamides with good to excellent yields.

K2S2O8-promoted aryl thioamides synthesis from aryl aldehydes using thiourea as the sulfur source

Thiourea as a sulfur atom transfer reagent was applied for the synthesis of aryl thioamides through a three-component coupling reaction with aryl aldehydes and N,N-dimethylformamide (DMF) or N,N-dimethylacetamide (DMAC). The reaction could tolerate various functional groups and gave moderate to good yields of desired products under the transition-metal-free condition.