634-19-5

Usage

Chemical Description

THF is tetrahydrofuran, a polar aprotic solvent.

Upstream product

• 108299-04-3 3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-carboxylic acid 
• 118-92-3 anthranilic acid 
• 88-67-5 2-Iodobenzoic acid 
• 3282-32-4 2-diazo-acetophenone 
• 89490-05-1 cyclohex-1-enylboronic acid 
• 610-97-9 o-iodo-methyl-benzoic acid 

Related news

Investigation of THF (cas 634-19-5) hydrate formation kinetics: Experimental measurements of volume changes07/19/2019

The present study is based on the investigation of hydrate formation and growth of THF through an online and direct method. In fact, the volume rise associated with hydrate formation has been used for kinetics studies. This procedure which is called volumetric method is more precise than the con...detailed

The influence of electric field and peroxide of THF (cas 634-19-5) on the THF (cas 634-19-5) hydrate formation07/15/2019

Natural gas hydrate (NGH) has great potential for exploitation, which is a new, clean and effective energy. THF hydrate has properties similar to methane hydrate. Hence, is widely researched to provide fundamental properties about hydrates. In this study, an experiment about THF hydrate formatio...detailed

Relevant academic research and scientific papers

Palladium-catalyzed intramolecular aromatic C-H acylation of 2-arylbenzoyl fluorides

The catalytic intramolecular cyclization of acyl fluorides using a Pd(OAc)2/PCy3 system is described. A wide range of 2-arylbenzoyl fluoride derivatives can be used as fluorenone precursors and the reaction proceeds via an intramolecular coupling between aromatic C-H bonds with acyl C-F bonds. The reaction can be applied to the synthesis of indenofluorenedione derivatives and to the construction of other molecules with fivemembered rings.

Intramolecular Vinylation of Aryl Rings by Vinyl Cations

A Lewis acid mediated intramolecular electrophilic vinylation of aryl rings by vinyl cations is reported. This reaction takes advantage of β-hydroxy-α-diazo ketones as vinyl cation precursors and provides good yields of tricyclic 1-indenones that contain

Direct carbocyclizations of benzoic acids: Catalyst-controlled synthesis of cyclic ketones and the development of tandem aHH (acyl Heck-Heck) reactions

The formation of exo-methylene indanones and indenones from simple ortho-allyl benzoic acid derivatives has been developed. Selective formation of the indanone or indenone products in these reactions is controlled by choice of ancillary ligand. This new process has a low environmental footprint as the products are formed in high yields using low catalyst loadings, while the only stoichiometric chemical waste generated from the reactants in the transformation is acetic acid. The conversion of the active cyclization catalyst into the Hermman-Beller palladacycle was exploited in a one-pot tandem acyl Heck-Heck (aHH) reaction, and utilized in the synthesis of donepezil. Carboxylic acids in aHH: Simple ortho-allyl benzoic acid derivatives have been utilized in an acyl Heck (aH) reaction to selectively form indanones and indenones. The conversion of the active cyclization catalyst into the Hermman-Beller palladacycle was exploited in a one-pot tandem acyl Heck-Heck (aHH) reaction to form two sp 2-sp2 bonds of (E)-trisubstituted olefins.