63407-43-2

Usage

Main properties

Chemical compound
Contains a 2-propenamide group and a 2-bromo-N-(4-methoxyphenyl) group
Used in organic synthesis and pharmaceutical research
Potential biological and pharmacological activities
Reactivity and interaction with biological targets
Studied for potential drug candidate or precursor in organic compound synthesis
Handle with caution due to potential hazards

Specific content

2-propenamide group
2-bromo-N-(4-methoxyphenyl) group
Potential biological and pharmacological activities
Reactivity and interaction with biological targets
Potential drug candidate or precursor in organic compound synthesis
Hazardous material, handle with caution

Upstream product

• 104-94-9 4-methoxy-aniline 
• 41965-71-3 α-bromoacryloyl chloride 

Relevant academic research and scientific papers

Anionic Bisoxazoline Ligands Enable Copper-Catalyzed Asymmetric Radical Azidation of Acrylamides

Asymmetric radical azidation for the synthesis of chiral alkylazides remains a tremendous challenge in organic synthesis. We report here an unprecedented highly enantioselective radical azidation of acrylamides catalyzed by 1 mol % of a copper catalyst. The substrates were converted to the corresponding alkylazides in high yield with good-to-excellent enantioselectivity. Notably, employing an anionic cyano-bisoxazoline (CN-Box) ligand is crucial to generate a monomeric CuII azide species, rather than a dimeric CuII azide intermediate, for this highly enantioselective radical azidation.

Nematicidal alkenanilides

A method is described for the control of nematodes in agricultural crops which comprises applying to the situs of infestation a nematicidal composition containing as active ingredient a compound of the formula STR1 wherein R1 and R2 are hydrogen, lower alkyl, or halogen, X is hydrogen or halogen, n is 1 or 2, Y is hydrogen, lower alkyl, halogen, trifluoromethyl, lower alkoxy, lower alkylthio, and nitro when n is 1, and halogen when n is 2, with the proviso that at least 1 of R1, R2, and X must be halogen. Preparation of active ingredient compounds is described, and nematicidal utility of compositions is exemplified.