41965-71-3 Usage
Description
2-Bromo-2-Propenoyl Chloride is a highly reactive chemical compound that falls into the classification of Acid Halides, more specifically, Bromo Acid Chlorides. It is known for its volatility and extreme reactivity with water, which makes it a useful chemical in industrial applications. However, its harmful nature when swallowed or inhaled, and its potential to cause severe burns and eye damage, necessitate careful handling and storage in effective containers under controlled conditions.
Uses
Used in Chemical Synthesis:
2-Bromo-2-Propenoyl Chloride is used as a key intermediate in the synthesis of various organic compounds. Its high reactivity allows it to participate in a wide range of chemical reactions, making it a valuable component in the production of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Bromo-2-Propenoyl Chloride is used as a building block for the synthesis of complex drug molecules. Its reactivity enables the formation of new chemical bonds, which can lead to the development of novel therapeutic agents with improved efficacy and safety profiles.
Used in Agrochemical Industry:
2-Bromo-2-Propenoyl Chloride is employed as a precursor in the synthesis of agrochemicals, such as pesticides and herbicides. Its ability to form new chemical entities makes it a crucial component in the development of innovative products that can help address challenges in agriculture, such as pest resistance and crop protection.
Used in Specialty Chemicals Production:
In the production of specialty chemicals, 2-Bromo-2-Propenoyl Chloride is used as a versatile reagent for the synthesis of various high-value compounds. Its unique properties allow it to be incorporated into a wide array of applications, including materials science, polymer chemistry, and the development of advanced technologies.
Check Digit Verification of cas no
The CAS Registry Mumber 41965-71-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,9,6 and 5 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 41965-71:
(7*4)+(6*1)+(5*9)+(4*6)+(3*5)+(2*7)+(1*1)=133
133 % 10 = 3
So 41965-71-3 is a valid CAS Registry Number.
41965-71-3Relevant articles and documents
Anionic Bisoxazoline Ligands Enable Copper-Catalyzed Asymmetric Radical Azidation of Acrylamides
Wu, Lianqian,Zhang, Zhihan,Wu, Dunqi,Wang, Fei,Chen, Pinhong,Lin, Zhenyang,Liu, Guosheng
, p. 6997 - 7001 (2021/02/26)
Asymmetric radical azidation for the synthesis of chiral alkylazides remains a tremendous challenge in organic synthesis. We report here an unprecedented highly enantioselective radical azidation of acrylamides catalyzed by 1 mol % of a copper catalyst. The substrates were converted to the corresponding alkylazides in high yield with good-to-excellent enantioselectivity. Notably, employing an anionic cyano-bisoxazoline (CN-Box) ligand is crucial to generate a monomeric CuII azide species, rather than a dimeric CuII azide intermediate, for this highly enantioselective radical azidation.
Cobalt(III)-Catalyzed Directed C-H Allylation
Gensch, Tobias,Vásquez-Céspedes, Suhelen,Yu, Da-Gang,Glorius, Frank
supporting information, p. 3714 - 3717 (2015/08/18)
The cobalt(III)-catalyzed allylation was developed for amide-directed C-H activation of arenes, heteroarenes, and olefins. A variety of allyl sources can be employed to introduce this useful functional group.
A novel synthesis of (-)-huperzine A via tandem intramolecular aza-Prins cyclization-cyclobutane fragmentation
White, James D.,Li, Yang,Kim, Jungchul,Terinek, Miroslav
supporting information, p. 882 - 885 (2013/03/28)
The acetylcholinesterase inhibitor (-)-huperzine A was synthesized from (S)-4-hydroxycyclohex-2-enone in 17 steps by a route that involved two cyclobutane fragmentations. The first of these employed a retro-aldol cleavage to generate the α-pyridone ring o
