634151-29-4

Upstream product

• 634151-27-2 2-(2-bromo-phenyl)-N-[2-(4-hydroxy-3-methoxy-phenyl)-ethyl]-acetamide 
• 18698-97-0 ortho-bromophenylacetic acid 
• 634151-28-3 1-(2-bromobenzyl)-6-methoxy-3,4-dihydroisoquinolin-7-ol 

Downstream Products

• 22222-86-2 1-Hydroxy-2-methoxyaporphin 
• 57256-36-7 1-benzyl-7-hydroxy-6-methoxy-1,2,3,4-tetrahydroisoquinoline 
• 634151-26-1 1-(2-bromobenzyl)-7-hydroxy-6-methoxy-3,4-dihydro-1H-isoquinoline-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Total synthesis method of natural product phenanthrene type alkaloid glycoside compound H4

To the total synthesis method of the natural product phenanthroline compound H4, 3 - methoxy -4 -hydroxyphenyethylamine hydrochloride is used as a starting raw material, 11-step reaction is carried out in sequence, and an acid amine condensation reaction

Intramolecular ortho-arylation of phenols utilized in the synthesis of the aporphine alkaloids (±)-lirinidine and (±)-nuciferine

A palladium-mediated intramolecular phenol ortho-arylation reaction applied to the construction of aporphine alkaloids is reported. Most significantly, the efficiency of this transformation was enhanced by the utilization of trialkylphosphine (i.e. tricyc