63416-65-9Relevant articles and documents
Functional Characterization of a Novel Series of Biased Signaling Dopamine D3 Receptor Agonists
Xu, Wei,Wang, Xiaozhao,Tocker, Aaron M.,Huang, Peng,Reith, Maarten E. A.,Liu-Chen, Lee-Yuan,Smith, Amos B.,Kortagere, Sandhya
, p. 486 - 500 (2017/03/20)
Dopamine receptors play an integral role in controlling brain physiology. Importantly, subtype selective agonists and antagonists of dopamine receptors with biased signaling properties have been successful in treating psychiatric disorders with a low inci
4-Hydroxy-1,3-benzenedimethanol derivatives
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, (2008/06/13)
Compounds of the general formula (I): STR1 in which one or more substituents R1 may be present and in which: R1 represents a halogen atom, preferably fluorine or chlorine, or a trifluoromethyl group or a group --NR5 R6 in which R5 and R6 which may be the same or different represent a hydrogen atom, or an alkyl group containing from 1 to 6 carbon atoms, preferably 1 to 4 carbon atoms or an acyl group, preferably the residue of a C1 -C6 alkanoic acid; X represents a straight or branched chain alkyl group containing 2 to 6 carbon atoms; and R2 and R3 which may be the same or different each represent a hydrogen atom or an alkyl group containing from 1 to 4 carbon atoms, preferably a methyl group; and R4 represents a hydrogen atom or an alkyl group containing 1 to 4 carbon atoms, are provided together with processes for the production thereof. They have a β2 -stimulant activity.