634192-53-3Relevant academic research and scientific papers
THERAPEUTIC COMPOUNDS
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Paragraph 0378; 0379, (2018/08/30)
The invention provides compounds of formula Ia′, Ib′, Ic′, and Id′: and pharmaceutically acceptable salts thereof, wherein the variables A, R6, R7, R8, R9, Rx, L, X, Y, and Z have the meaning as described herein. The compounds are useful for reducing endoplasmic reticulum stress and for producing analgesia in an animal.
HYDROXY-BIPHENYL-CARBALDEHYDE OXIME DERIVATIVES AND THEIR USE AS ESTROGENIC AGENTS
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Page 18; 37, (2008/06/13)
This invention provides estrogen receptor modulators having the structure formula (I): wherein R1 to R6 and R8 are as defined in the specification; or a pharmaceutically acceptable salt thereof.
ERbeta ligands. Part 1: the discovery of ERbeta selective ligands which embrace the 4-hydroxy-biphenyl template.
Edsall Jr., Richard J,Harris, Heather A,Manas, Eric S,Mewshaw, Richard E
, p. 3457 - 3474 (2007/10/03)
The synthesis and structure-activity relationships of a series of simple biphenyls is described. Optimization of the 4-hydroxy-biphenyl template led to compounds with ERbeta selectivity on the order of 20-70-fold.
2-(2,6-dichlorophenyl)-diarylimidazoles
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Page/Page column 9, (2010/11/29)
The invention is directed to compounds of formula (I), which are valuable therapeutics for the treatment of cancer and related diseases.
