634196-45-5Relevant academic research and scientific papers
Synthesis and transformations of (imidazolylimino)thiazolidinones
El'tsov,Mokrushin,Bel'skaya,Kozlova
, p. 461 - 466 (2003)
The reaction of ethyl 5-phenylthioureido-3H-imidazole-4-carboxylate with bromoacetic acid afforded (imidazolylimino)thiazolidinones, which were transformed into the corresponding 5-arylidene-4-thiazolidinones by the reactions with aldehydes. Under the conditions of the Knoevenagel reaction, the thiazolidine ring in derivatives of 4-(4-oxothiazolidin-2-ylidene-amino)-3H- imidazole-4-carboxamides was opened to form substituted guanidines.
Synthesis of novel derivatives of 2-(azolylimino)thiazoline
Eltsov,Mokrushin,Tkachev
, p. 2293 - 2302 (2007/10/03)
Successive alkylation of 5-(3-phenylthioureido)-3H-imidazole-4-carboxamides with alkyl halides and chloroacetone gave (N-oxopropylimidazolyl)isothioureas, which were easily converted into derivatives of purine and imidazopyrazinone. In the case of ethyl 5
