634197-75-4Relevant academic research and scientific papers
A programmable one-pot oligosaccharide synthesis for diversifying the sugar domains of natural products: A case study of vancomycin
Ritter, Thomas K.,Mong, Kwok-Kong T.,Liu, Haitian,Nakatani, Takuji,Wong, Chi-Huey
, p. 4657 - 4660 (2003)
The notoriously difficult glycosylation of vancomycin was tackled in a one-pot procedure. A number of oligosaccharides were synthesized and attached to the vancomycin aglycon to create a library of derivatives (see formula) to probe the effect of glycosylation on the antibiotic activity.
