6342-48-9

Basic information

• Product Name: CAS 6342-48-9
• CAS NO: 6342-48-9
• Molecular Formula: C₁₄H₁₃N₃O₂
• Molecular Weight: 255.276
• Mol File: 6342-48-9.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: CAS 6342-48-9(CAS DataBase Reference)
• NIST Chemistry Reference: CAS 6342-48-9(6342-48-9)
• EPA Substance Registry System: CAS 6342-48-9(6342-48-9)

Safety Data

• Hazardous Substances Data: 6342-48-9(Hazardous Substances Data)

Usage

General Description

CAS 6342-48-9 refers to 2,3,7,8-Tetrachlorodibenzo-p-dioxin, a highly toxic and persistent organic pollutant. This chemical is a type of dioxin, which is a group of toxic compounds known for their harmful effects on human health and the environment. 2,3,7,8-Tetrachlorodibenzo-p-dioxin is classified as a human carcinogen and has been linked to a range of health issues, including reproductive and developmental problems, immune system suppression, and skin disorders. It is also known to bioaccumulate in the food chain, making it a significant environmental concern. Due to its extreme toxicity and long-lasting effects, efforts to control and eliminate this chemical are ongoing.

Upstream product

• 54-85-3 isoniazid 
• 135-02-4 ortho-anisaldehyde 

Downstream Products

• 1372893-02-1 C₂₅H₂₆ClN₅O₂ 
• 1372893-01-0 (25Z)-N-(1-[2-{3-[(dimethylamino)methyl]-2-methoxyphenyl}-5-(pyridin-4-yl)-1,3,4-oxadiazol-3(2H)-yl]ethylidene)-4-fluorobenzenamine 
• 1372893-00-9 C₂₅H₂₆FN₅O₂ 
• 1372892-99-3 C₂₅H₂₆FN₅O₂ 
• 1372892-98-2 (19Z)-N-(1-[2-{3-[(dimethylamino)methyl]-2-methoxyphenyl}-5-(pyridin-4-yl)-1,3,4-oxadiazol-3(2H)-yl]ethylidene)benzenamine 
• 1372892-97-1 1-(2-(3-((dimethylamino)methyl)-2-methoxyphenyl)-5-(pyridin-4-yl)-1,3,4-oxadiazol-3(2H)-yl)ethanone 
• 1372893-13-4 (25Z)-N-(1-[2-{3-[(dimethylamino)methyl]-2-methoxyphenyl}-5-(pyridin-4-yl)-1,3,4-oxadiazol-3(2H)-yl]ethylidene)-4-methoxybenzenamine 
• 1372893-12-3 C₂₆H₂₉N₅O₃ 
• 1372893-11-2 C₂₆H₂₉N₅O₃ 
• 1372893-10-1 (25Z)-N-(1-[2-{3-[(dimethylamino)methyl]-2-methoxyphenyl}-5-(pyridin-4-yl)-1,3,4-oxadiazol-3(2H)-yl]ethylidene)-4-nitrobenzenamine 
• 1372893-09-8 C₂₅H₂₆N₆O₄ 
• 1372893-08-7 C₂₅H₂₆N₆O₄ 
• 1372893-07-6 (19Z)-N-(1-[2-{3-[(dimethylamino)methyl]-2-methoxyphenyl}-5-(pyridin-4-yl)-1,3,4-oxadiazol-3(2H)-yl]ethylidene)-4-bromobenzenamine 
• 1372893-06-5 C₂₅H₂₆BrN₅O₂ 

Relevant articles and documents

Investigation of nicotinamide and isonicotinamide derivatives: A quantitative and qualitative structural analysis

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An efficient alkynylation of 4-thiazolidinone with terminal alkyne under C-H functionalisation

A method of palladium catalysed efficient alkynylation through the cross coupling reaction of terminal alkynes with the slightly more acidic C-H bonds of 4-thiazolidinone has been developed. This method allows the direct introduction of an ethynyl group into the 4-thiazolidinone moiety. Mild reaction conditions involving aerial oxidation and one pot synthesis make this reaction more efficient for the formation of sp3(C)-sp(C) bond.

New oxadiazole derivatives of isonicotinohydrazide in the search for antimicrobial agents: Synthesis and in vitro evaluation

Structural modifications of the front line antitubercular drug isoniazid provide lipophilic adaptations of the drug in which the hydrazide moiety of isoniazid is replaced by 1,3,4-oxadiazole heterocycles to eliminate in vivo acetylation by arylamine N-ace