6344-63-4

Basic information

• Product Name: 1-AMINOFLUORENE
• Synonyms: 1-FLUORENAMINE;1-AMINOFLUORENE;TIMTEC-BB SBB000229;9H-Fluoren-1-amine;Fluoren-1-amine;Fluorene, 1-amino-;Fluorenes/Biphenyls;1-Aminofluorene 99%
• CAS NO: 6344-63-4
• Molecular Formula: C₁₃H₁₁N
• Molecular Weight: 181.23
• Mol File: 6344-63-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 125-126 °C(lit.)
• Boiling Point: 358.3 °C at 760 mmHg
• Flash Point: 188.8 °C
• Appearance: /
• Density: 1.203 g/cm³
• PKA: 4.40±0.20(Predicted)
• CAS DataBase Reference: 1-AMINOFLUORENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-AMINOFLUORENE(6344-63-4)
• EPA Substance Registry System: 1-AMINOFLUORENE(6344-63-4)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• RTECS: LL5074000
• Hazardous Substances Data: 6344-63-4(Hazardous Substances Data)

Usage

Uses

9H-Fluoren-1-amine is an intermediate used in the synthesis of Fluoren-1-ol (F462450), which is a metabolite of the PAH micropollutant Fluorene (F462002) with potential mutagenic effects. It is used as biomarkers to evaluate exposure to PAHs and environmental tobacco smoke in general population. Photoluminescent dye.

General Description

1-Aminofluorene is pyrolysis product of 4-phenyl-oxindole.

InChI:InChI=1S/C13H11N/c14-13-7-3-6-11-10-5-2-1-4-9(10)8-12(11)13/h1-7H,8,14H2

Upstream product

• 22250-99-3 1-nitrofluorene 
• 7235-17-8 1-Oximino-1,2,3,4-tetrahydro-fluoren 
• 88909-93-7 fluorene-1-carbonyl azide 
• 55341-64-5 9H-fluorene-1-carboxyl chloride 
• 6276-03-5 9H-fluorene-1-carboxylic acid 
• 28314-03-6 N-(9H-fluoren-1-yl)acetamide 
• 6344-62-3 1-amino-9H-fluoren-9-one 
• 28314-06-9 fluoren-1-yl-carbamic acid ethyl ester 
• 855623-83-5 fluoren-1-yl isocyanate 
• 63019-65-8 1-Diacetylamino-fluoren 
• 6954-57-0 N-(9-oxo-fluoren-1-yl)-acetamide 

Downstream Products

• 22250-99-3 1-nitrofluorene 
• 343-38-4 8-Fluor-2-nitrofluoren 
• 1224702-73-1 4β-(1''-fluorenylamino)-4-desoxypodophyllotoxin 
• 1224702-79-7 4'-O-demethyl-4β-(1''-fluorenylamino)-4-desoxypodophyllotoxin 
• 28314-03-6 N-(9H-fluoren-1-yl)acetamide 
• 22251-01-0 N-hydroxyl-1-fluorenylacetamide 
• 26060-14-0 1-Methoxyfluoren 
• 109747-39-9 benzylidene-fluoren-1-yl-amine 
• 343-25-9 1-fluoro-9H-fluorene 

Relevant articles and documents

Method for reducing carbonyl reduction to methylene under illumination

The invention belongs to the technical field of organic chemical synthesis. The method comprises the following steps: (1) mixing the carbonyl compound and the amine compound in a solvent, reacting 3 - 6 under the illumination of 380 - 456 nm, the reaction system is low in toxicity, high in atom utilization rate 12 - 24h. and production efficiency, safe and controllable in reaction process and capable of simplifying the operation in the preparation and production process. At the same time, the residue toxicity of the reaction is minimized, the pollution caused by the production process to the environment is reduced, and the steps and operations of removing residues after the reaction are simplified. In addition, the reactant feedstock is readily available. The reactant does not need additional modification before the reaction, can be directly used for preparing production, simplifies the operation steps, and shortens the reaction route. The production cost is obviously reduced.

Route to the tritiation of carbon atom 9 of carcinogenic fluorenylhydroxamic acids

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