6276-03-5

Basic information

• Product Name: 1-FLUORENECARBOXYLIC ACID
• Synonyms: FLUORENE-1-CARBOXYLIC ACID;9H-FLUORENE-1-CARBOXYLIC ACID;1-FLUORENECARBOXYLIC ACID
• CAS NO: 6276-03-5
• Molecular Formula: C₁₄H₁₀O₂
• Molecular Weight: 210.23
• EINECS: 228-472-5
• Product Categories: Fluorenes;Fluorenes & Fluorenones;C13 to C42+;Carbonyl Compounds;Carboxylic Acids;Building Blocks;C13 to C42+;Carbonyl Compounds;Carboxylic Acids;Chemical Synthesis;Organic Building Blocks
• Mol File: 6276-03-5.mol
• Article Data: 5

Chemical Properties

• Melting Point: 246-248 °C(lit.)
• Boiling Point: 100 °C / 12mmHg
• Flash Point: 185.4 °C
• Appearance: /
• Density: 1.306 g/cm³
• Vapor Pressure: 1.43E-07mmHg at 25°C
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: soluble in Tetrahydrofuran
• PKA: 4.11±0.20(Predicted)
• CAS DataBase Reference: 1-FLUORENECARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 1-FLUORENECARBOXYLIC ACID(6276-03-5)
• EPA Substance Registry System: 1-FLUORENECARBOXYLIC ACID(6276-03-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 22-24/25-36/37/39-27-26
• WGK Germany: 3
• Hazardous Substances Data: 6276-03-5(Hazardous Substances Data)

Usage

Chemical Properties

Light brown powder

Uses

1-Fluorenecarboxylic Acid is an intermediate used in the synthesis of Fluoren-1-ol (F462450), which is a metabolite of the PAH micropollutant Fluorene (F462002) with potential mutagenic effects. It is used as biomarkers to evaluate exposure to PAHs and environmental tobacco smoke in general population. Also, it possesses interface electronic properties. Achiral fluorescent agent.

InChI:InChI=1/C14H10O2/c15-14(16)12-7-3-6-11-10-5-2-1-4-9(10)8-13(11)12/h1-7H,8H2,(H,15,16)/p-1

Upstream product

• 7446-70-0 aluminium trichloride 
• 71-43-2 benzene 
• 76-03-9 trichloroacetic acid 
• 86-73-7 9H-fluorene 
• 124-38-9 carbon dioxide 
• 206-44-0 fluoranthene 
• 1573-92-8 9-oxo-9H-fluorene-1-carboxylic acid 
• 7732-18-5 water 

Downstream Products

• 81699-50-5 fluorene-1-carboxylic acid ethyl ester 
• 86-73-7 9H-fluorene 
• 124-38-9 carbon dioxide 
• 333793-49-0 N-[3-(4,5-dimethylimidazol-1-yl)-phenyl]-9H-fluorene-1-carboxamide 
• 333793-47-8 N-[3-(4-methylimidazol-1-yl)-phenyl]-9H-fluorene-1-carboxamide 
• 403987-28-0 C₃₉H₃₅N₃O₂ 
• 55341-64-5 9H-fluorene-1-carboxyl chloride 
• 28314-03-6 N-(9H-fluoren-1-yl)acetamide 
• 91651-26-2 7-Nitro-9-oxo-fluoren-1-carbonsaeure 
• 65817-53-0 1-amino-7-nitrofluorene 
• 26060-14-0 1-Methoxyfluoren 
• 6344-63-4 1-aminofluorene 
• 88909-93-7 fluorene-1-carbonyl azide 
• 122269-88-9 1-chloro-FM-bar-Phe-OMe 

Relevant articles and documents

Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives

The present invention is related to chemical compositions, processes for the preparation thereof and uses of the composition. Particularly, the present invention relates to compositions of compounds of Formula (A): wherein Ar, Y, R1 and q are as defined herein; and their use in the treatment of diseases, including treatment of sleepiness, promotion of wakefulness, treatment of Parkinson's disease, cerebral ischemia, stroke, sleep apneas, eating disorders, stimulation of appetite and weight gain, treatment of attention deficit hyperactivity disorder ("ADHD"), enhancing function in disorders associated with hypofunctionality of the cerebral cortex, including, but not limited to, depression, schizophrenia, fatigue, in particular, fatigue associated with neurologic disease, such as multiple sclerosis, chronic fatigue syndrome, and improvement of cognitive dysfunction.

Pigment composition

A pigment composition contains a pigment and a dispersant. The dispersant is a polyester compound which contains, per molecule, a residuum of at least two benzene rings coupled together, an aromatic ring having at least 8 carbon atoms or a heterocyclic ring having at least 8 carbon atoms, and at least one ester bond as a principal bond.