634465-89-7

Basic information

• Product Name: 4-Piperidinecarbonitrile, 4-[2-(trifluoromethyl)phenyl]-, monohydrochloride
• CAS NO: 634465-89-7
• Molecular Formula: C13H13F3N2.ClH
• Molecular Weight: 290.716
• Mol File: 634465-89-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Piperidinecarbonitrile, 4-[2-(trifluoromethyl)phenyl]-, monohydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Piperidinecarbonitrile, 4-[2-(trifluoromethyl)phenyl]-, monohydrochloride(634465-89-7)
• EPA Substance Registry System: 4-Piperidinecarbonitrile, 4-[2-(trifluoromethyl)phenyl]-, monohydrochloride(634465-89-7)

Safety Data

• Hazardous Substances Data: 634465-89-7(Hazardous Substances Data)

Upstream product

• 634465-94-4 tert-butyl 4-cyano-4-[2-(trifluoromethyl)phenyl]-1-piperidinecarboxylate 

Downstream Products

• 634467-92-8 1-(2-chloroacetyl)-4-[2-(trifluoromethyl)phenyl]-4-piperidinecarbonitrile 

Relevant articles and documents

Piperazinylacylpiperidine derivatives, their preparation and therapeutic use thereof

The invention relates to substituted 1-piperazinylacylpiperidine derivatives of general formula (I) in which: n is 1 or 2; p is 1 or 2; R1 represents a halogen atom; a trifluoromethyl radical; a (C1-C4)alkyl; a (C1-C4)alkoxy; a trifluoromethoxy radical; R2 represents a hydrogen atom or a halogen atom; R3 represents a hydrogen atom; a group —OR5; a group —CH2OR5; a group —NR6R7; a group —NR8COR9; a group —NR8CONR10R11; a group —CH2NR12R13; a group —CH2NR8CONR14R15; a (C1-C4)alkoxycarbonyl; a group —CONR16R17; or else R3 constitutes a double bond between the carbon atom to which it is attached and the adjacent carbon atom of the piperidine ring; R4 represents an aromatic group selected from: the said aromatic groups being unsubstituted or being mono- or disubstituted by a substituent selected independently from a halogen atom; a (C1-C4)alkyl; a (C1-C4)alkoxy; a trifluoromethyl radical; Preparation process and therapeutic application.