634465-94-4

Basic information

• Product Name: 1-BOC-4-CYANO-4-(2-TRIFLUOROMETHYLPHENYL)-PIPERIDINE
• Synonyms: 1-BOC-4-CYANO-4-(2-TRIFLUOROMETHYLPHENYL)-PIPERIDINE;1-Boc-4-cyano-4-(2-CF3-phenyl)piperidine
• CAS NO: 634465-94-4
• Molecular Formula: C₁₈H₂₁F₃N₂O₂
• Molecular Weight: 354.37
• Mol File: 634465-94-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 432.9±45.0 °C(Predicted)
• Appearance: /
• Density: 1.23±0.1 g/cm3(Predicted)
• PKA: -3.63±0.40(Predicted)
• CAS DataBase Reference: 1-BOC-4-CYANO-4-(2-TRIFLUOROMETHYLPHENYL)-PIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BOC-4-CYANO-4-(2-TRIFLUOROMETHYLPHENYL)-PIPERIDINE(634465-94-4)
• EPA Substance Registry System: 1-BOC-4-CYANO-4-(2-TRIFLUOROMETHYLPHENYL)-PIPERIDINE(634465-94-4)

Safety Data

• Hazardous Substances Data: 634465-94-4(Hazardous Substances Data)

Usage

Chemical Class

Belongs to the piperidine class of molecules

Physical Appearance

White to off-white solid

Usage in Organic Synthesis

Used as a building block to create various chemical compounds

Pharmaceutical Industry Application

Used as an intermediate in the production of drugs

Field of Application

Medicinal chemistry

Role in Drug Development

Key ingredient in the development of new therapeutic agents

Upstream product

• 118753-70-1 N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine 
• 3038-47-9 2-(trifluoromethyl)phenylacetonitrile 

Downstream Products

• 634465-89-7 4-[2-(trifluoromethyl)phenyl]-4-piperidinecarbonitrile hydrochloride 
• 191328-19-5 4-cyano-4-(2-trifluoromethylphenyl)piperidine 

Relevant articles and documents

Piperazinylacylpiperidine derivatives, their preparation and therapeutic use thereof

The invention relates to substituted 1-piperazinylacylpiperidine derivatives of general formula (I) in which: n is 1 or 2; p is 1 or 2; R1 represents a halogen atom; a trifluoromethyl radical; a (C1-C4)alkyl; a (C1-C4)alkoxy; a trifluoromethoxy radical; R2 represents a hydrogen atom or a halogen atom; R3 represents a hydrogen atom; a group —OR5; a group —CH2OR5; a group —NR6R7; a group —NR8COR9; a group —NR8CONR10R11; a group —CH2NR12R13; a group —CH2NR8CONR14R15; a (C1-C4)alkoxycarbonyl; a group —CONR16R17; or else R3 constitutes a double bond between the carbon atom to which it is attached and the adjacent carbon atom of the piperidine ring; R4 represents an aromatic group selected from: the said aromatic groups being unsubstituted or being mono- or disubstituted by a substituent selected independently from a halogen atom; a (C1-C4)alkyl; a (C1-C4)alkoxy; a trifluoromethyl radical; Preparation process and therapeutic application.