634583-48-5Relevant academic research and scientific papers
Synthesis and α-mannosidase inhibitory evaluation of (2R,3R,4S)- and (2S,3R,4S)-2-(aminomethyl)pyrrolidine-3,4-diol derivatives
Popowycz, Florence,Gerber-Lemaire, Sandrine,Rodriguez-Garcia, Eliazar,Schuetz, Catherine,Vogel, Pierre
, p. 1914 - 1948 (2003)
The synthesis of 46 derivatives of (2R,3R,4S)-2-(aminomethyl)pyrrolidine-3,4-diol is reported (Scheme 1 and Fig. 3), and their inhibitory activities toward α-mannosidases from jack bean (B) and almonds (A) are evaluated (Table). The most-potent inhibitors
