634902-31-1

Upstream product

• 2393-23-9 4-methoxy-benzylamine 
• 110104-60-4 (E)-4-chloro-3-methoxy-but-2-enoic acid methyl ester 
• 142274-06-4 ethyl (E)-4-chloro-3-methoxy-2-butenoate 

Downstream Products

• 634902-32-2 1-(4-methoxybenzyl)pyrrolidine-2,4-dione 
• 937166-58-0 4-methoxy-1-(4-methoxy-benzyl)-2-trimethylsilanyloxy-1H-pyrrole 
• 1026614-79-8 (S)-5-Benzyl-1-(4-methoxy-benzyl)-pyrrolidine-2,4-dione 
• 634902-30-0 4-[(S)-2-(1-methoxy-1-ethylpropyl)pyrrolidin-1-yl]-1-(4-methoxybenzyl)-2,5-dihydro-1H-2-azolone 
• 634902-46-8 (5S)-4-[(S)-2-(1-methoxy-1-ethylpropyl)pyrrolidin-1-yl]-1-(4-methoxybenzyl)-5-benzyl-2,5-dihydro-1H-2-azolone 
• 1099824-78-8 C₁₈H₂₃NO₄ 
• 1099824-77-7 1-(4-methoxybenzyl)-4-methoxy-5,5-bis(3-oxopentyl)-1H-pyrrol-2(5H)-one 
• 1099824-62-0 2,2,2-trifluoroethyl 3-[1-(4-methoxybenzyl)-2,5-dihydro-3-methoxy-5-oxo-1H-pyrrol-2-yl]propanoate 
• 1099824-63-1 bis(2,2,2-trifluoroethyl) 3,3'-[1-(4-methoxybenzyl)-2,5-dihydro-3-methoxy-5-oxo-1H-pyrrole-2,2-diyl]dipropanoate 
• 1099824-75-5 (2E)-diethyl 2-[1-(4-methoxybenzyl)-2,5-dihydro-3-methoxy-5-oxo-1H-pyrrol-2(5H)-ylidene]fumarate 

Relevant academic research and scientific papers

Direct-type vinylogous Mukaiyama-Michael addition reactions involving pyrrolinone donors

The direct Mukaiyama-Michael addition of vinylogous tetramate donors to a number of different Michael acceptors has been easily executed, by employing the TMSOTf/Et3N mixture as soft Lewis acid/base promoter agent. Richly functionalized, highly

Compounds and Uses Thereof - 848

This invention relates to novel compounds having the structural formula I below: and their pharmaceutically acceptable salts, tautomers or in vivo-hydrolysable precursors, compositions and methods of use thereof, wherein R1, R2, Rsu

4,5-erythro/5,6-threo-Stereoselectivity in vinylogous Mukaiyama aldol addition of a silyloxypyrrole to a threose derivative: stereochemical rationalization and relevance to (+)-castanospermine synthesis

Vinylogous Mukaiyama aldol addition of N-p-methoxybenzyl-4-methoxy-2-trimethylsilyloxypyrrole 7 to bis-MOM threose 6 using SnCl4 as promoter gave the 4,5-erythro/5,6-threo adduct 8, with the correct absolute configurations for the castanospermi

A Flexible Approach to (S)-5-Alkyl Tetramic Acid Derivatives: Application to the Asymmetric Synthesis of (+)-Preussin and Protected (3S,4S)-AHPPA

(Equation presented) A flexible asymmetric approach to 5-alkyl tetramic acid derivatives is described, which is based on the use of 9 as the first synthetic equivalent to chiral nonracemic tetramic acid 5-carbanionic synthon 9b. The existence of the carbanion intermediate 9b was proven by trapping with trimethylchlorosilane. Application of the present method to the synthesis of antifungal alkaloid (+)-preussin, as well as protected (3S,4S)-AHPPA 6, is also described.