635283-75-9Relevant academic research and scientific papers
"Cascade-release dendrimers" liberate all end groups upon a single triggering event in the dendritic core
De Groot, Franciscus M. H.,Albrecht, Carsten,Koekkoek, Ralph,Beusker, Patrick H.,Scheeren, Hans W.
, p. 4490 - 4494 (2007/10/03)
A single triggering event in the core of a dendrimer composed of two or more generations of multiple-release monomeric building blocks can induce the release of all end groups at the termini of the dendrimer (see schematic representation). Such multiple-release systems could find application, for example, in the field of (targeted) drug delivery, where a disease- or organ-specific activation event could trigger simultaneous release of multiple biologically active molecules.
