635291-69-9

Upstream product

• 22509-74-6 N-ethoxycarbonylphthalimide 

Downstream Products

• 635291-78-0 (S)-2-[(2S,3S)-2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-5-hydroxy-3-phenyl-pentanoyl]-pyrazolidine-1,3-dicarboxylic acid 1-benzyl ester 3-methyl ester 
• 635291-70-2 methyl 1-benzyloxycarbonyl-2-[2-(1,3-di-oxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpent-4-enoyl]pyrazolidine-3-carboxylate 
• 635291-76-8 methyl (3S)-2-[(2S,3S)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenyl-5-oxopentanoyl]-1-benzyloxycarbonylpyrazolidine-3-carboxylate 

Relevant academic research and scientific papers

Constrained peptidomimetics: Building bicyclic analogs of pyrazoline derivatives

A synthetic route has been developed for incorporating pyrazoline derivatives as proline surrogates in constrained X-Pro peptidomimetics. The route allows for the synthesis of dipeptide building blocks having either a six or seven-membered-ring annulated