635304-58-4

Upstream product

• 929431-57-2 p-(methanesulfonyloxy)propiophenone 

Downstream Products

• 1173444-33-1 2-{benzyl-[2-(4-benzyloxyphenyl)-ethyl]-amino}-1-(4-hydroxy-phenyl)-propan-1-one 
• 1185253-43-3 2-{benzyl-[2-(4-benzyloxyphenyl)-ethyl]-amino}-1-(4-hydroxy-phenyl)-propan-1-one hydrochloride 
• 1345518-18-4 4-(2-{benzyl-[2-(4-benzyloxyphenyl)-ethyl]-amino}-propionyl)phenyl methanesulfonate 
• 635304-59-5 (2S)-1-[4-(methanesulfonyloxy)phenyl]-2-[((1R)-phenylethyl)amino]-1-propanone 

Relevant academic research and scientific papers

METHOD FOR PREPARING RITODRINE HYDROCHLORIDE

The present invention describes a new method for preparing Ritodrinehydrochloride.The invention also concerns non-hygroscopic crystalline polymorphic Ritodrine hydrochloride Form (I).

PROCESS FOR PRODUCING OPTICALLY ACTIVE s-AMINO ALCOHOL

A process for easily producing an optically active β-amino alcohol useful as a pharmaceutical intermediate from an inexpensive, readily available starting material is provided. A readily available α-substituted ketone is reacted with an optically active amine to yield a diastereomer mixture of an optically active α-substituted aminoketone. One of the diastereomers is isolated optionally after the diastereomers are converted to salts with an acid. The optically active α-substituted aminoketone or a salt thereof thus isolated was stereoselectively reduced to yield an optically active β-substituted amino alcohol. The optically active β-substituted amino alcohol is subjected to hydrogenolysis to produce an optically active β-amino alcohol or a salt thereof.