929431-57-2

Basic information

• Product Name: p-(methanesulfonyloxy)propiophenone
• Synonyms: p-(methanesulfonyloxy)propiophenone
• CAS NO: 929431-57-2
• Molecular Weight: 228.269
• Mol File: 929431-57-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: p-(methanesulfonyloxy)propiophenone(CAS DataBase Reference)
• NIST Chemistry Reference: p-(methanesulfonyloxy)propiophenone(929431-57-2)
• EPA Substance Registry System: p-(methanesulfonyloxy)propiophenone(929431-57-2)

Safety Data

• Hazardous Substances Data: 929431-57-2(Hazardous Substances Data)

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 70-70-2 4-hydroxypropiophenone 

Downstream Products

• 635304-58-4 1-[4-(methanesulfonyloxy)phenyl]-2-bromo-1-propanone 
• 1345518-18-4 4-(2-{benzyl-[2-(4-benzyloxyphenyl)-ethyl]-amino}-propionyl)phenyl methanesulfonate 
• 1185253-43-3 2-{benzyl-[2-(4-benzyloxyphenyl)-ethyl]-amino}-1-(4-hydroxy-phenyl)-propan-1-one hydrochloride 
• 1173444-33-1 2-{benzyl-[2-(4-benzyloxyphenyl)-ethyl]-amino}-1-(4-hydroxy-phenyl)-propan-1-one 

Relevant articles and documents

PROCESS FOR PRODUCING OPTICALLY ACTIVE s-AMINO ALCOHOL

A process for easily producing an optically active β-amino alcohol useful as a pharmaceutical intermediate from an inexpensive, readily available starting material is provided. A readily available α-substituted ketone is reacted with an optically active amine to yield a diastereomer mixture of an optically active α-substituted aminoketone. One of the diastereomers is isolated optionally after the diastereomers are converted to salts with an acid. The optically active α-substituted aminoketone or a salt thereof thus isolated was stereoselectively reduced to yield an optically active β-substituted amino alcohol. The optically active β-substituted amino alcohol is subjected to hydrogenolysis to produce an optically active β-amino alcohol or a salt thereof.