63591-88-8Relevant academic research and scientific papers
Metal-free intermolecular C-O cross-coupling reactions: Synthesis of: N -hydroxyimide esters
Lv, Yunhe,Sun, Kai,Pu, Weiya,Mao, Shukuan,Li, Gang,Niu, Jiejie,Chen, Qian,Wang, Tingting
, p. 93486 - 93490 (2016)
Selectfluor-mediated intermolecular C-O cross coupling reaction for the synthesis of N-hydroxyimide esters was developed for the first time. The reaction is applicable to the coupling of readily available aryl and alkyl aldehydes with N-hydroxyphthalimide (NHPI) and N-hydroxysuccinimide (NHSI). The resulting active esters can be directly converted into amides in one pot.
Transition-Metal-Free, Visible-Light-Enabled Decarboxylative Borylation of Aryl N-Hydroxyphthalimide Esters
Candish, Lisa,Teders, Michael,Glorius, Frank
supporting information, p. 7440 - 7443 (2017/06/13)
Herein, we report a conceptually novel borylation reaction proceeding via a mild photoinduced decarboxylation of redox-activated aromatic carboxylic acids. This work constitutes the first application of cheap and easily prepared N-hydroxyphthalimide esters as aryl radical precursors and does not require the use of expensive transition metals or ligands. The reaction is operationally simple, scalable, and displays broad scope and functional group tolerance.
Organocatalytic amidation and esterification of aldehydes with activating reagents by a cross-coupling strategy
Tan, Bin,Toda, Narihiro,Barbas III, Carlos F.
supporting information, p. 12538 - 12541 (2013/02/22)
Formation on demand: An organocatalytic cross-coupling reaction of aldehydes with N-hydroxyimides, hexafluoroisopropyl alcohol, and sulfonimides has been developed. The resulting active intermediates can be directly converted into amides or esters in one pot. This simple method makes use of readily available starting materials, and the newly discovered activating reagents should find broad application in the synthesis of amides and esters. Copyright
