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3-Hydroxy-4-phenylbut-3-en-2-one, also known as 3-hydroxy-4-phenyl-3-buten-2-one or simply 3-HPB, is an organic compound characterized by a molecular formula of C10H10O2. This molecule features a 3-hydroxy group (-OH), a 4-phenyl group (C6H5), and a 3-buten-2-one structure. It is a colorless to pale yellow crystalline solid with a melting point of approximately 70-72°C. 3-HPB is an important intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds due to its unique structure and reactivity. It can be synthesized through various methods, including aldol condensation, Claisen condensation, and other organic reactions. The compound is sensitive to light and heat, and it is typically stored under cool, dark conditions to maintain its stability.

6362-60-3

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6362-60-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6362-60-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,6 and 2 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 6362-60:
(6*6)+(5*3)+(4*6)+(3*2)+(2*6)+(1*0)=93
93 % 10 = 3
So 6362-60-3 is a valid CAS Registry Number.

6362-60-3Relevant academic research and scientific papers

[1,3]-Claisen rearrangement via removable functional group mediated radical stabilization

Alam, Md Nirshad,Dash, Soumya Ranjan,Mukherjee, Anirban,Pandole, Satish,Marelli, Udaya Kiran,Vanka, Kumar,Maity, Pradip

supporting information, p. 890 - 895 (2021/02/01)

A thermal O-to-C [1,3]-rearrangement of α-hydroxy acid derived enol ethers was achieved under mild conditions. The 2-aminothiophenol protection of carboxylic acids facilitates formation of the [1,3] precursor and its thermal rearrangement via stabilization of a radical intermediate. Experimental and theoretical evidence for dissociative radical pair formation, its captodative stability via aminothiophenol, and a unique solvent effect are presented. The aminothiophenol was deprotected from rearrangement products as well as after derivatization to useful synthons.

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