63628-26-2 Usage
Uses
Used in Synthetic Chemistry:
(R)-(-)-2-METHOXY-2-(1-NAPHTHYL)PROPIONIC ACID is used as a building block for the synthesis of more complex organic structures, leveraging its unique structural features and chirality to create novel compounds with specific properties.
Used in Stereochemistry:
In the field of stereochemistry, (R)-(-)-2-METHOXY-2-(1-NAPHTHYL)PROPIONIC ACID is utilized for studying and understanding the spatial arrangement of atoms in molecules, which is crucial for the development of enantiomerically pure compounds with distinct biological activities.
Used in Pharmaceutical Industry:
(R)-(-)-2-METHOXY-2-(1-NAPHTHYL)PROPIONIC ACID is used as an intermediate in the synthesis of pharmaceutical compounds, where its chiral nature can contribute to the development of drugs with improved efficacy and selectivity.
Used in Material Science:
(R)-(-)-2-METHOXY-2-(1-NAPHTHYL)PROPIONIC ACID can be employed in the development of new materials with specific optical, electronic, or mechanical properties, taking advantage of its structural features and chirality.
It is important to handle (R)-(-)-2-METHOXY-2-(1-NAPHTHYL)PROPIONIC ACID with care, as exposure and ingestion may pose health risks. Suitable precautions and protective measures should be taken during its use in various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 63628-26-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,6,2 and 8 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 63628-26:
(7*6)+(6*3)+(5*6)+(4*2)+(3*8)+(2*2)+(1*6)=132
132 % 10 = 2
So 63628-26-2 is a valid CAS Registry Number.
InChI:InChI=1/C14H14O3/c1-14(17-2,13(15)16)12-9-5-7-10-6-3-4-8-11(10)12/h3-9H,1-2H3,(H,15,16)/t14-/m1/s1
63628-26-2Relevant articles and documents
Enantioresolution of 2-methoxy-2-(1-naphtyl)propionic acid using diastereomeric salt formation with chiral phenylethylamine
Kusakari, Miho,Ohta, Yurie,Nakagawa, Hideaki,Katagiri, Hiroshi,Kijima, Tatsuro,Murakami, Satoshi,Matsuba, Shigeru,Hatano, Bunpei
supporting information, p. 4114 - 4116 (2014/07/22)
An enantioresolution of 2-methoxy-2-(1-naphtyl)propionic acid (MαNP acid) using the diastereomeric salt with chiral (R)-phenylethylamine was achieved to give enantiopure (R)-MαNP acid in 29% yield with >99% ee based on rac-MαNP acid. X-ray crystallographi
2-Methoxy-2-(1-naphthyl)propionic acid, a powerful chiral auxiliary for enantioresolution of alcohols and determination of their absolute configurations by the 1H NMR anisotropy method
Harada, Nobuyuki,Watanabe, Masataka,Kuwahara, Shunsuke,Sugio, Akinori,Kasai, Yusuke,Ichikawa, Akio
, p. 1249 - 1253 (2007/10/03)
Racemic 2-methoxy-2-(1-naphthyl)propionic acid (1, MαNP acid) was enantioresolved as its esters derived from various chiral alcohols. For example, a diastereomeric mixture of esters prepared from (±)-1 and (1R,3R,4S)-(-)-menthol was easily separated by HP
