6363-17-3Relevant academic research and scientific papers
New compounds for inhibiting differentiation of osteoclast and pharmaceutical composition comprising thereof
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, (2014/02/16)
New compounds and pharmaceutical compositions comprising active ingredients having inhibition effects on osteoclast differentiation are provided. The pharmaceutical compositions comprising the new compounds can be used as medicines for treating metabolic bone diseases such as bone metastatic cancer, solid cancer bone metastasis, musculoskeletal complication by solid cancer bone metastasis, hypercalcemia by malignant tumor, multiple myeloma, primary bone tumor, osteoporosis, rheumatoid arthritis, osteoarthritis, periodontal disease, inflammatory resorption of alveolar bone, inflammatory resorption of bone, and Paget's disease.
Investigation of a transition metal-assisted retro Diels-Alder reaction used in the synthesis of transition metal S2O complexes
Urove, Greg A.,Welker, Mark E.,Eaton, Bruce E.
, p. 105 - 114 (2007/10/02)
Treatment of 4,5-diphenyl-3,6-dihydro-1,2-dithiin-1-oxide with coordinatively unsaturated transition metal complexes resulted in the production of S2O complexes and 2,3-diphenylbutadiene.A transition metal-assisted retro Diels-Alder mechanism has been proposed for this reaction.A series of IR and 1H NMR experiments and MNDO calculations on 4,5-diphenyl-3,6-dihydro-1,2-dithiin-1-oxide have been performed to gain additional information about this transformation.
110. Synthesis of 1H-Cyclopropanaphthalenes via Trapping of o-Benzoquinodimethanes
Mueller, Paul,Rodriguez, Domingo
, p. 975 - 980 (2007/10/02)
1H-Cyclopropanaphthalene (10a) and 3-methyl or dimethyl derivatives have been synthesized by interception of appropriately substituted o-quinodimethanes 3 with 1-bromo-2-chlorocyclopropene 5, and subsequent dehydrohalogenation of the adducts.The o-quin
