6364-17-6Relevant articles and documents
Squaric acid: an impressive organocatalyst for the synthesis of biologically relevant 2,3-dihydro-1H-perimidines in water
Khopkar, Sushil,Shankarling, Ganapati
, (2020/01/30)
Abstract: Squaric acid, a green, metal-free and eco-friendly organocatalyst, has been exploited for the synthesis of biologically interesting 2,3-dihydro-1H-perimidines. The reaction was performed using water as a green reaction medium and the organocatal
COMPOUNDS FOR THE DETECTION OF SENESCENT CELLS
-
Page/Page column 58; 59; 63, (2018/02/03)
The present disclosure relates to de novo synthesized, chemical compounds of the formula (1) or (2) that function as senescent cell detectors wherein R1, R2, R3, R4 and Z are as defined herein. The present invention also relates to processes for the preparation of these compounds, to their use in the detection of senescent cells, to methods of detecting senescence in cells and to kits comprising said compounds. The compounds have the ability to react with lipofuscin, in an analogous manner to the histochemical dye Sudan Black B (SBB).
Perimidine derivative and application thereof
-
Paragraph 0056; 0057; 0058, (2018/04/26)
The invention provides a compound of general formulae (I) and (II), wherein A1 and A2 are independently selected from C1-12 alkyl, C6-60 substituted or unsubstituted aryl and C10-60 substituted or unsubstituted condensed ring aryl, separately; the substituted aryl specifically means that the substituent is selected from C1-6 alkyl, halogen and CN or Si(R2)3, and R2 is selected from C1-6 alkyl; andthe substituted condensed ring aryl specifically means that the substituent is selected from C1-6 alkyl, halogen and CN or Si(R2)3, and R2 is selected from C1-6 alkyl. The compound of the general formulae can be used in organic electroluminescence devices.