6364-17-6

Usage

General Description

2,2-dimethyl-2,3-dihydro-1H-perimidine is a chemical compound with the molecular formula C9H14N2. It is a bicyclic organic compound that contains a pyrimidine ring structure with two methyl groups attached to the carbon atoms. 2,2-dimethyl-2,3-dihydro-1H-perimidine has been studied for its potential use in pharmaceuticals and agrochemicals due to its unique structure and potential functional properties. It has been shown to exhibit biological activity and could be useful in the development of new drugs or pesticides. Additionally, its distinct molecular structure makes it a valuable target for synthetic chemistry research and the development of new chemical reactions.

InChI:InChI=1/C13H14N2/c1-13(2)14-10-7-3-5-9-6-4-8-11(15-13)12(9)10/h3-8,14-15H,1-2H3

Upstream product

• 123-54-6 acetylacetone 
• 479-27-6 naphthalene-1,8-diamine 
• 67-64-1 acetone 

Downstream Products

• 64482-94-6 2,3-dihydro-1,2,2,3-tetramethyl-1H-perimidine 
• 204-02-4 1-H-perimidine 
• 479-27-6 naphthalene-1,8-diamine 
• 925446-80-6 perimidine-9-carbaldehyde 

Relevant academic research and scientific papers

Squaric acid: an impressive organocatalyst for the synthesis of biologically relevant 2,3-dihydro-1H-perimidines in water

Abstract: Squaric acid, a green, metal-free and eco-friendly organocatalyst, has been exploited for the synthesis of biologically interesting 2,3-dihydro-1H-perimidines. The reaction was performed using water as a green reaction medium and the organocatal

Chitosan hydrochloride mediated efficient, green catalysis for the synthesis of perimidine derivatives

Chitosan hydrochloride as biopolymer-based, renewable, and recyclable heterogeneous catalyst was used for efficient one-pot synthesis of perimidine derivatives. This newly developed greener methodology provides a very simple and greener route for the synt

COMPOUNDS FOR THE DETECTION OF SENESCENT CELLS

The present disclosure relates to de novo synthesized, chemical compounds of the formula (1) or (2) that function as senescent cell detectors wherein R1, R2, R3, R4 and Z are as defined herein. The present invention also relates to processes for the preparation of these compounds, to their use in the detection of senescent cells, to methods of detecting senescence in cells and to kits comprising said compounds. The compounds have the ability to react with lipofuscin, in an analogous manner to the histochemical dye Sudan Black B (SBB).

COMPOUNDS, LINKED WITH HAPTENS, FOR THE DETECTION OF SENESCENT CELLS

The present disclosure relates to compounds of the formula (1) that function as senescent cell detectors: wherein the SBB analogues refer to de novo synthesized derivatives with structural similarity to the Sudan Black B dye, L is an appropriate chemical bond and hapten is biotin, or digoxigenin, or 2,4-dinitrophenol, or fluorescein, but more preferably biotin. The present invention also relates to processes for the preparation of these compounds, to their use in the detection of senescent cells, to methods of detecting senescence in cells and to kits comprising said compounds.

Perimidine derivative and application thereof

The invention provides a compound of general formulae (I) and (II), wherein A1 and A2 are independently selected from C1-12 alkyl, C6-60 substituted or unsubstituted aryl and C10-60 substituted or unsubstituted condensed ring aryl, separately; the substituted aryl specifically means that the substituent is selected from C1-6 alkyl, halogen and CN or Si(R2)3, and R2 is selected from C1-6 alkyl; andthe substituted condensed ring aryl specifically means that the substituent is selected from C1-6 alkyl, halogen and CN or Si(R2)3, and R2 is selected from C1-6 alkyl. The compound of the general formulae can be used in organic electroluminescence devices.

Perimidine derivatives and application thereof

The invention provides perimidine derivatives as shown in general formulas (1) and (2) which are described in the specification. In the formulas, L and L are independently selected from a groupconsisting of substituted or unsubstituted C6-C30 arylene groups and substituted or unsubstituted C6-C30 heteroarylene groups, and the substituents of the C6-C30 arylene groups and the C6-C30 heteroarylene groups are selected from a group consisting of C1-C6 alkyl groups, halogen and CN.

Perimidine derivative and application thereof

The invention provides a general formula compound. The general formula compound is represented by a general formula (I) and (II) (shown in the description), wherein A1 and A2 are respectively independently selected from C6-C60 substituted aryl or fused-ring aryl, and C4-C60 substituted or unsubstituted heteroaryl or fused heterocyclic aryl; substituent groups on alkyl, aryl and the fused-ring arylare respectively independently selected from monocyclic or fused-ring aryl having a hetero atom selected from B, N, O, S, P(=O), Si and P and having 4 to 60 ring carbon atoms; substituent groups on the heteroaryl and the fused heterocyclic aryl are respectively independently selected from F, Cl, Br, I, CHO, CN and NO2, or selected from C1 to C30 alkyl, cycloalkyl, alkenyl, alkoxy or thio-alkoxy,or selected from the monocyclic or fused-ring aryl having a hetero atom selected from B, N, O, S, P(=O), Si and P and having 4 to 60 ring carbon atoms. The general formula compound provided by the invention can be applied to organic electroluminescence devices.

Perimidine derivative

The present invention relates to a perimidine derivative, discloses an organic electroluminescent compound and uses of the organic electroluminescent compound in preparation of organic electroluminescent devices, and further provides an organic electroluminescence device, which comprises the organic electroluminescent compound. According to the present invention, the organic electroluminescent compound can effectively reduce the working voltage of the organic electroluminescent device and improve the luminous efficiency of the organic electroluminescent device.

Visible light photoredox catalysis: Aerobic oxidation of perimidines to perimidinones

Aerobic oxidation of a series of 2,3-dihydro-1H-perimidines to the corresponding 4- and 6-perimidinones via visible light photoredox catalysis using Ru(bpy)32+ as a catalyst was reported. The scope and limitation of this oxidation were investigated and a possible photochemical mechanism was proposed.

Dye compound and method of making the compound

A perimidine coupler of formula 1: where R and R′ are substituents independently selected from the group consisting of a hydrogen atom, C1 to C4 alkyl or a solubilizing moiety comprising a substituted or unsubstituted C10 to C70 hydrocarbyl group. At least one of R and R′ is not a hydrogen atom or C1 to C4 alkyl. R″ and R′″ can be independently selected from the group consisting of a hydrogen atom, C1 to C6 alkyl groups and halogens.