636608-03-2

Basic information

• Product Name: 1H-Indole, 1-[(2-bromo-4,5-dimethoxyphenyl)methyl]-2,3-dihydro-
• CAS NO: 636608-03-2
• Molecular Formula: C17H18BrNO2
• Molecular Weight: 348.239
• Mol File: 636608-03-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1H-Indole, 1-[(2-bromo-4,5-dimethoxyphenyl)methyl]-2,3-dihydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole, 1-[(2-bromo-4,5-dimethoxyphenyl)methyl]-2,3-dihydro-(636608-03-2)
• EPA Substance Registry System: 1H-Indole, 1-[(2-bromo-4,5-dimethoxyphenyl)methyl]-2,3-dihydro-(636608-03-2)

Safety Data

• Hazardous Substances Data: 636608-03-2(Hazardous Substances Data)

Upstream product

• 428501-02-4 ethyl 2-(2-(azidomethyl)phenyl)acetate 
• 2859-78-1 4-Bromoveratrole 
• 39191-76-9 ethyl 2-(2-(bromomethyl)phenyl)acetate 
• 1394134-41-8 1-(2-bromo-4,5-dimethoxybenzyl)indolin-2-one 
• 4385-35-7 isochroman-3-one 
• 40851-64-7 2-(2-(azidomethyl)phenyl)acetic acid 
• 496-15-1 1-indoline 
• 53207-00-4 1-bromo-2-(bromomethyl)-4,5-dimethoxybenzene 

Downstream Products

• 65367-74-0 oxoassoanine 
• 107208-75-3 Assoanine 

Relevant articles and documents

Schmidt Reaction of ω-Azido Valeryl Chlorides Followed by Intermolecular Trapping of the Rearrangement Ions: Synthesis of Assoanine and Related Pyrrolophenanthridine Alkaloids

The Schmidt reaction of ω-azido valeryl chlorides in the presence of an additional nucleophile was explored. The arenes, alcohols, and amines were demonstrated as the intermolecular trapping reagents for isocyanate ion and N-acyliminium ion from the Schmidt rearrangement, affording the corresponding products with moderate to excellent yields. Two 2-oxoindoles from the reaction were successfully converted into four natural alkaloids, namely, assoanine, anhydrolycorine, oxoassoanine, and anhydrolycorinone.