65367-74-0

Basic information

• Product Name: 9,10-dimethoxy-1,2,3,12,15,16-hexadehydrogalanthan-7-one
• Synonyms: 9,10-Dimethoxy-1,2,3,12,15,16-hexadehydrogalanthan-7-one
• CAS NO: 65367-74-0
• Molecular Formula: C₁₇H₁₅NO₃
• Molecular Weight: 281.3059
• Mol File: 65367-74-0.mol

Chemical Properties

• Boiling Point: 510.7°C at 760 mmHg
• Flash Point: 262.7°C
• Density: 1.35g/cm³
• Vapor Pressure: 1.51E-10mmHg at 25°C
• Refractive Index: 1.672
• CAS DataBase Reference: 9,10-dimethoxy-1,2,3,12,15,16-hexadehydrogalanthan-7-one(CAS DataBase Reference)
• NIST Chemistry Reference: 9,10-dimethoxy-1,2,3,12,15,16-hexadehydrogalanthan-7-one(65367-74-0)
• EPA Substance Registry System: 9,10-dimethoxy-1,2,3,12,15,16-hexadehydrogalanthan-7-one(65367-74-0)

Safety Data

• Hazardous Substances Data: 65367-74-0(Hazardous Substances Data)

Upstream product

• 88660-15-5 1-(2-amino-4,5-dimethoxybenzoyl)-indoline 
• 636608-03-2 1-(2-bromo-4,5-dimethoxybenzyl)-2,3-dihydroindole 

Downstream Products

• 80787-57-1 pratorinine 

Relevant articles and documents

Concise synthesis of pyrrolophenanthridine alkaloids using a Pd-mediated biaryl coupling reaction with regioselective C-H activation via the intramolecular coordination of the amine to Pd

The concise synthesis of Amaryllidaceae alkaloids, such as anhydrolycorinone, anhydrolycorin-7-one, assoanine, and oxoassoanine, which have a pyrrolophenanthridine skeleton, was achieved in moderate yield using the Pd-mediated biaryl coupling reaction of

Synthetic studies on pyrrolophenanthridone skeleton from 1-benzoyl-7-iododihydroindole derivatives using palladium-assisted biaryl coupling reactions

The biaryl coupling reaction of 1-benzoyl-7-iododihydroindole derivatives using Pd reagent was examined. 1-[(1,3-Benzodioxol-5-yl)carbonyl]-7-iodo-2,3-dihydroindole gave 4,5-dihydro-7H-[1,3]dioxolo[4,5-k]pyrrolo[3,2,1-de] phenanthridin-7-one, which was formed by connection to a more hindered carbon, as a major product. 1-(3,4-Dimethoxybenzoyl)-7-iodo-2,3-dihydroindole gave oxoassoanine and 10,11-dimethoxy-4,5-dihydropyrrolo[3,2,1-de]-phenanthridin-7-one in an almost equal ratio.

Concise synthesis of pyrrolophenanthridine alkaloids using a Pd-catalyzed biaryl coupling reaction with regioselective C-H activation

The concise synthesis of the pyrrolophenanthridine alkaloids such as anhydrolycorine, assoanine, anhydrolycorin-7-one, and oxoassoanine, was achieved using the Pd-catalyzed biaryl coupling reaction of 1-(2-halobenzyl)-2,3-dihydroindole by applying the regioselective C-H activation method with intramolecular coordination of the benzylamino group to Pd.