63664-41-5

Basic information

• Product Name: Butanamide, 3-oxo-N-(1-phenylethyl)-, (R)-
• CAS NO: 63664-41-5
• Molecular Formula: C12H15NO2
• Molecular Weight: 205.257
• Mol File: 63664-41-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Butanamide, 3-oxo-N-(1-phenylethyl)-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanamide, 3-oxo-N-(1-phenylethyl)-, (R)-(63664-41-5)
• EPA Substance Registry System: Butanamide, 3-oxo-N-(1-phenylethyl)-, (R)-(63664-41-5)

Safety Data

• Hazardous Substances Data: 63664-41-5(Hazardous Substances Data)

Upstream product

• 141-97-9 ethyl acetoacetate 
• 618-36-0 rac-methylbenzylamine 
• 1694-31-1 tert-butyl acetoacetate 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 5394-63-8 2,2,6-trimethyl-4H-1,3-dioxin-4-one 
• 674-82-8 4-methyleneoxetan-2-one 

Downstream Products

• 88996-69-4 3-Methyl-1,4-dioxy-quinoxaline-2-carboxylic acid ((R)-1-phenyl-ethyl)-amide 
• 1005459-66-4 (R,R)-N-(1-phenylethyl)-4-(2-chloro-4-fluorophenyl)-6-methyl-2-(2-thiazolyl)-1,4-dihydropyrimidin-5-carboxamide 
• 1203506-46-0 N₃-[(1R)-1-Phenylethyl]-6-chloro-2-methyl-4-phenyl-3-quinolinecarboxamide 
• 1005459-79-9 R,R-N-(1-phenylethyl)-4-(2-chloro-4-fluorophenyl)-2-(2,4,6-trifluorophenyl)-6-methyl-1,4-dihydropyrimidine-5-carboxamide 
• 139952-19-5 (+)-N-(1(R)-phenylethyl)-3(S)-tert-butyldimethylsilyloxybutyramide 
• 139952-18-4 (+)-N-(1(R)-phenylethyl)-3(R)-tert-butyldimethylsilyloxybutyramide 
• 139952-17-3 (+)-N-(1(R)-phenylethyl)-3(S)-hydroxybutyramide 
• 88996-83-2 3-Methyl-quinoxaline-2-carboxylic acid ((R)-1-phenyl-ethyl)-amide 
• 139952-17-3 N-(1-phenylethyl)-3-hydroxybutyramide 

Relevant articles and documents

An efficient synthesis of enantiopure (R)-heteroarylpyrimidine Analogs

An efficient synthesis of enantiopure (R)-heteroarylpyrimidine analogs is described here, which involves introduction of a chiral group, formation and separation of diasteroisomers and final transformation of an amide to an ester. The absolute configuration of the enantiopure HAPs is confirmed by X-ray analysis of their intermediates.

Optically Pure Dihydropyrimidine Compounds and Their Uses for the Preparation of a Medicament for Treatment and Prevention of Viral Diseases

The present invention relates to an optically pure compound of formula (I) or a pharmaceutically acceptable salt or hydrate thereof, a process for preparing the optically pure compound of formula (I), and use of the optically pure compound of formula (I)

Lipase-catalyzed aminolysis and ammonolysis of β-ketoesters. Synthesis of optically active β-ketoamides.

Aminolysis and ammonolysis reactions of β-ketoesters catalyzed by Candida antarctica lipase are very efficient methods for the preparation of β- ketoamides. When racemic amines are used in these processes, the corresponding optically active β-ketoamides are obtained with moderate-high enantiomeric excesses.