636987-22-9Relevant academic research and scientific papers
Microwave-Assisted Condensation of Benzylic Alcohols and Alkynes Promoted by Zinc Halides: Concise Access to Alkenyl Halides
Goel, Komal,Nandi, Poulomi,Satyanarayana, Gedu,Sreenivasulu, Chinnabattigalla
, p. 4851 - 4860 (2021/11/17)
A simple Lewis acid-mediated route for the synthesis of alkenyl halides are described under microwave-assisted conditions. The reaction proceeds through the condensation between secondary alcohols and terminal acetylenes and regioselective hydrohalogenati
Highly enantioselective conjugate addition of diethylzinc to acyclic enones with fine-tunable phosphite-pyridine ligands
Wan, Huihui,Hu, Yuanchun,Liang, Yuxue,Gao, Shuang,Wang, Junwei,Zheng, Zhuo,Hu, Xinquan
, p. 8277 - 8280 (2007/10/03)
A new series of fine-tunable phosphite-pyridine (P,N) ligands derived from (S)-2-amino-2′-hydroxy-6,6′-dimethyl-1,1′-biphenyl and (S)-2-amino-2′-hydroxy-4,4′,6,6′-tetramethyl-1, 1′-biphenyl was employed in Cu(I)-catalyzed conjugate addition of diethylzinc
Effect of InCl3 on the addition of Grignard reagents to α,β-unsaturated carbonyl compounds
Kelly, Brian G.,Gilheany, Declan G.
, p. 887 - 890 (2007/10/03)
Control of 1,2- versus 1,4-addition of organometallic reagents to enones remains a long-standing problem. There is still no satisfactory 1,2-directing agent comparable to the 1,4-directing effect of copper salts. We report that the presence of just 5 mol% indium(III) chloride can significantly alter the amount of 1,2-product formed in these reactions.
Optically active bipyridines in nickel catalyzed enantioselective conjugate addition to enones
Bolm,Ewald
, p. 5011 - 5012 (2007/10/02)
In the presence of catalytic amounts of Ni(acac)2 and a chiral bipyridine, diethyl zinc adds enantioselectively to enones to give optically active β-substituted ketones in good yields.
