637-39-8

Basic information

• Product Name: TRIETHANOLAMINE HYDROCHLORIDE
• Synonyms: TRIETHANOLAMINE HCL;TRIHYDROXYTRIETHYLAMINE HYDROCHLORIDE;TRIETHYLOLAMINE HYDROCHLORIDE;TRIETHANOLAMINE HYDROCHLORIDE;2,2',2'-NITRILITRIETHANOL HYDROCHLORIDE;2,2',2''-NITRILOTRIETHANOL HYDROCHLORIDE;2,2’,2’’-nitrilotri-ethanohydrochloride;2,2’,2’’-nitrilotris-ethanohydrochloride
• CAS NO: 637-39-8
• Molecular Formula: C₆H₁₆NO₃*Cl
• Molecular Weight: 185.65
• EINECS: 211-284-2
• Mol File: 637-39-8.mol
• Article Data: 15

Chemical Properties

• Melting Point: 177-179 °C(lit.)
• Boiling Point: 335.4 °C at 760 mmHg
• Flash Point: 185 °C
• Appearance: /
• Density: 1.354[at 20℃]
• Vapor Pressure: 8.38E-06mmHg at 25°C
• Storage Temp.: Store at RT.
• Solubility: H2O: 1 M at 20 °C, clear, colorless
• PKA: 7.8(at 25℃)
• Water Solubility: Soluble in water.
• Sensitive: Hygroscopic
• Merck: 14,9665
• BRN: 3909940
• CAS DataBase Reference: TRIETHANOLAMINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: TRIETHANOLAMINE HYDROCHLORIDE(637-39-8)
• EPA Substance Registry System: TRIETHANOLAMINE HYDROCHLORIDE(637-39-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 22-24/25-36-26
• WGK Germany: 1
• RTECS: KL9346500
• F: 3
• TSCA: Yes
• Hazardous Substances Data: 637-39-8(Hazardous Substances Data)

Usage

Chemical Properties

White/clear crystalline powder

Uses

Protein purification reagent Triethanolamine hydrochloride serves as a protein purification reagent, an emulsifier and a surfactant. It is used in the study of chemical cross linking of chloroplast coupling factor and acts as a medium for assaying adenosine diphosphate (ADP). It acts as an organic additive in the grinding of cement clinker and as a complexing agent for aluminum ions in aqueous solutions. It is used for the neutralization of fatty acids and adjusting buffer pH as well as utilized to dissolve oils.

Definition

ChEBI: A hydrochloride obtained by combining triethanolamine with one equivalent of hydrogen chloride.

Flammability and Explosibility

Notclassified

Purification Methods

Crystallise the salt from EtOH. Dry it at 80o. [Beilstein 4 IV 1525.]

InChI:InChI=1/C6H15NO3.ClH/c8-4-1-7(2-5-9)3-6-10;/h8-10H,1-6H2;1H

Upstream product

• 326-91-0 1,1,1-trifluoro-4-(2-thienyl)butane-2,4-dione 
• 102-71-6 triethanolamine 
• 107-07-3 2-chloro-ethanol 
• 541-41-3 chloroformic acid ethyl ester 

Downstream Products

• 110-91-8 morpholine 
• 109-01-3 1-methyl-piperazine 
• 1006-94-6 5-methoxylindole 
• 817-09-4 tris-(2-chloroethyl)amine hydrochloride 
• 102582-90-1 tris(2-hydroxyethyl)ammonium 4-nitrophenylsulfanylacetate 
• 102582-89-8 tris(2-hydroxyethyl)ammonium 4-methylphenylsulfonylacetate 
• 175178-88-8 2-(4-chlorophenylsulfonyl)acetate of tris(2-hydroxylethyl)ammonium 
• 112695-78-0 Tris-(2-hydroxyethyl)ammonium phenylselenoacetate 
• 1312670-97-5 2-hydroxy-N,N-bis(2-hydroxyethyl)ethaneammonium [(1-benzylindol-3-yl)sulfonyl]acetate 
• 55543-68-5 2-(2-methylphenyloxy)acetate of tris(2-hydroxyethyl)-ammonium 
• 7553-56-2 iodine 
• 27096-29-3 triethanolammonium nitrate 

Relevant articles and documents

Structural study of the coordination behavior of a tetradentate NO3-donor amino alcohol ligand toward a CdII:HgII mixture

In this work, the reaction of 2,2′,2″-nitrilotriethanol (NTE) with a 1:1 mixture of CdI2 and HgI2 is investigated. The complex [Cd(NTE)2][Hg2(μ-I)2I4] was synthesized and identified by elemental analysis, FT-IR, 1H NMR spectroscopy and single-crystal X-ray diffraction. The structure of the [HNTE]Cl salt is also presented. In the crystal structure of the complex, the cadmium atom has a CdN2O6 environment in a slightly distorted cube geometry. This geometry is one of the rare cube geometries with a minimum distortion among the Cambridge Structural Database structures for cadmium complexes. The anionic moiety has a binuclear structure with the mercury atoms being in tetrahedral environments. In the network of the complex, in addition to O-H ? I hydrogen bonds, there are I ? I interactions which lead to ten-membered rings.

Synthesis, physico-chemical and antimicrobial studies of ionic liquid

A novel ammonium salt, an ionic liquid (ILs) was synthesized at room temperature. Its structure was elucidated by elemental analyses and various spectroscopic techniques like FT-IR, 1H and 13C NMR and ESI-MS spectrometry. Thermal studies were also carried out to get thermal stability of the ionic compound. X-ray crystallographic study was carried out to ascertain the structure of ammonium cation which is bonded to three anion via O-H Cl intermolecular hydrogen bonds. Synthesized compound was also investigated for in vitro antimicrobial study against number microbes and results showed excellent results.

Synthesis, molecular structure, and vibrational spectra of tetrakis(2-hydroxyethylammonium) chloride and its triethanolamine precursor and metabolite

A unique one-stage synthesis of tetrakis(2-hydroxyethylammonium) salts, precursors of new hypervalent silicon compounds, has been developed. The vibration spectra of tetrakis(2-hydroxyethylammonium) chloride and its triethanolamine precursor and metabolite have been studied by IR spectroscopy and quantum chemistry. Analysis of alterations in the modes with increasing number of HOCH2CH2 groups has been performed.