1723-94-0

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 52, p. 467, 1987 DOI: 10.1021/jo00379a035

Upstream product

• 110-91-8 morpholine 
• 3240-94-6 N-(2-chlorethyl)morpholine 
• 106-93-4 ethylene dibromide 
• 637-39-8 triethanolamine hydrochloride 
• 107-15-3 ethylenediamine 
• 111-44-4 3-oxa-1,5-dichloropentane 
• 107-21-1 ethylene glycol 
• 107-06-2 1,2-dichloro-ethane 
• 151257-53-3 1,2-bis(1H-benzo[d][1,2,3]triazol-1-yl)-1,2-dimorpholinoethane 
• 140-07-8 2,2',2'',2'''-ethane-1,2-diylbisazanediyl-tetrakis-ethanol 
• 7529-22-8 4-methylmorpholine N-oxide 

Downstream Products

• 7702-61-6 3,12-dioxa-6,9-diazonia-dispiro[5.2.5.3]heptadecane; dibromide 
• 4394-85-8 4-morpholinecarboxaldehyde 

Relevant academic research and scientific papers

Selectivity Modulation of the Ley–Griffith TPAP Oxidation with N-Oxide Salts

A wide variety of novel non-hygroscopic N-oxide tetraphenylborate salts were synthesized and evaluated as co-oxidants in the Ley–Griffith (TPAP) oxidation of benzylic and allylic alcohols under non-anhydrous conditions. The novel DABCOO·TPB (2:1) salt was herein unearthed as a viable competitor to the first-generation NMO·TPB (2:1) salt, but more importantly gave increased performance under oxidative competition. X-ray crystal structure analysis and NMR spectroscopy revealed that depending on the crystallization conditions 1:1, 2:1 or 3:2 N-oxide–tetraphenylborate salts could be formed.

Visible-light photo-catalytic C-C bond cleavages: Preparations of N,N-dialkylformamides from 1,2-vicinal diamines

A range of 1,2-vicinal diamines were smoothly converted into N,N-dialkylformamides under the synergistic actions of Ru(bpy) 3Cl2 photo-catalyst, 45 W household lighting bulb, and Cs2CO3 basic additive under very mild reaction conditions. The process involves visible light-enabled photo-catalytic cleavage of C-C bond as the strategic event.

Radicals derived from N-methylmorpholine-N-oxide (NMMO): Structure, trapping and recombination reactions

The two carbon-centered radicals 4-morpholinomethyl (4) and 4-methylmorpholin-3-yl (5), generated from the primary cation radical intermediate 3 by β-deprotonation, are the major radical species in reaction mixtures of N-methylmorpholine-N-oxide (1) as de

A Novel Method for the Synthesis of Symmetrical Vicinal Tertiary and Secondary Diamines

A variety of symmetrical vicinal tertiary and secondary diamines are readily prepared in good to excellent yields by either Grignard reaction or reduction of the glyoxal bisproducts with benzotriazole and secondary or primary amines.

N-Alkylation d'amines en catalyse homogene. Synthese de mono- et de diamines cycliques

Ruthenium compounds are appropriate catalysts in the N-alkylation of amines.The synthesis of N-alkylated cyclic amines from a cyclic amine and an alcohol or via the condensation between a diol and a primary amine are described.The reaction with cyclic amines is highly selective, especially in the presence of a phosphine, making it a high yielding preparative procedure.The catalytic condensation between cyclic amines and diols yields either an aminoalcohol (A) or a bicyclic diamine (B).The temperature, the presence of phosphine, and the ratio of amine to diol are decisive in directing the reaction toward A or B.The proposed mechanism involves the dehydrogenation of the alcohol followed by attack of the amine on the aldehyde intermediate.

Homogeneously Catalyzed Synthesis of β-Amino Alcohols ans Vicinal Diamines from Ethylene Glycol and 1,2-Propanediol

Disubstituted β-amino alcohols and tetrasubstituted vicinal alkanediamines have been synthesized in high yield and at mild temperatures by the selective amination of ethylene glycol and 1,2-propanediol catalyzed by ruthenium or iridium complexes.