63701-36-0Relevant academic research and scientific papers
SYNTHESES AND ANTIBACTERIAL ACTIVITY OF SOME NEW N-(3-METHYL-2-QUINOXALOYL) AMINO ALCOHOLS AND AMINE 1,4-DIOXIDES.
Sabri,El-Abadelah,Owais
, p. 229 - 231 (2007/10/02)
The syntheses and in vitro and in vivo antibacterial activities of a series of N-(3-methyl-2-quinoxaloyl) amino alcohols and amine 1,4-dioxides, and their deoxygenated analogues, are described. The quinoxaline 1,4-dioxide derivative of the naturally occurring ( minus )-ephedrine was found to be the most potent antibacterial agent of the series. The presence of a hydroxy group and a tertiary amide appears to be associated with enhancement of the antibacterial action.
