63734-62-3

Usage

Uses

Used in Agricultural and Horticultural Industries:
3-(2-CHLORO-4-TRIFLUOROMETHYLPHENOXY)BENZOIC ACID is used as a herbicide for controlling broadleaf weeds in various crops. It functions by disrupting the growth hormones of the target plants, leading to their eventual death. As a selective herbicide, it targets specific types of plants without affecting others, often being combined with other herbicides to broaden the spectrum of weed control.

InChI:InChI=1/C14H8ClF3O3/c15-11-7-9(14(16,17)18)4-5-12(11)21-10-3-1-2-8(6-10)13(19)20/h1-7H,(H,19,20)

Upstream product

• 328-84-7 1,2-dichloro-4-(trifluoromethyl)benzene 
• 99-06-9 3-Carboxyphenol 
• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 121-17-5 2-chloro-3-nitro-5-trifluoromethylbenzene 
• 28286-79-5 3-(Hydroxymethyl)benzoic acid 

Downstream Products

• 50594-66-6 acifluorfen 
• 57025-79-3 2-chloro-5-(o-chloro-p-trifluoromethyl-phenoxy)-benzoic acid 
• 88185-22-2 1'-(ethoxycarbonyl)ethyl 3-(2-chloro-4-trifluoromethylphenoxy)benzoate 
• 63734-63-4 methyl 3-(2-chloro-4-trifluoromethylphenoxy)benzoate 
• 50594-67-7 5-[(2-chloro-α,α,α-trifluoro-p-tolyl)oxy]-2-nitrobenzoic acid,methyl ester 

Relevant academic research and scientific papers

Preparation process of acifluorfen

The invention relates to the technical field of herbicides, and discloses a preparation process of acifluorfen, which comprises the following steps: synthesizing 3-[2-chloro-4-(trifluoromethyl) phenoxy] benzoic acid by using 3, 4-dichlorobenzotrifluoride as a raw material, and carrying out nitration reaction by using concentrated sulfuric acid and concentrated nitric acid as mixed acids to obtainacifluorfen. According to the production process disclosed by the invention, an extracted 3-[2-chloro-4-(trifluoromethyl) phenoxy] benzoic acid solution is directly conveyed to a nitration kettle fornitration reaction, the process is simpler, the production progress can be effectively accelerated, the yield can be effectively increased, the nitration reaction temperature in the process is about 40 DEG C, the reaction time is shorter, the problem of more impurities caused by high temperature and overlong reaction time can be avoided, meanwhile, the time cost can also be saved, and the preparation process has the characteristics of mild reaction conditions and high yield.

Preparation method of 3-(2-chorine-4-trifluoromethyl) phenoxybenzoic acid

The invention provides a preparation method of 3-(2-chorine-4-trifluoromethyl) phenoxybenzoic acid, and belongs to the field of chemical synthesis. The preparation method has the advantages that the synthesizing process is free from impurities, so that the yield and the purity of a target product can be improved, and solid wastes are decreased. The preparation method is characterized in that m-hydroxybenzoic acid and sodium hydroxide are subjected to refluxing dehydrating in a solvent, and then a catalyst and 2-nitryl-4-trifluoromethyl chlorobenzene are added to react to obtain an intermediate 3-(2-nitryl-4-trifluoromethyl) phenoxybenzoic acid; the intermediate 3-(2-nitryl-4-trifluoromethyl) phenoxybenzoic acid is subjected to hydrogenation reduction and diazotization to obtain the target product 3-(2-chorine-4-trifluoromethyl) phenoxybenzoic acid. By virtue of the preparation method, three-position isomer is completely avoided; the raw materials are low in price and easy to obtain; the preparation method is easily industrially carried out.

Process for the preparation of diphenyl ether compounds

A process for producing fomesafen from acifluorfen comprises the steps of (a) converting acifluorfen to its acid chloride, (b) coupling the acid chloride so formed with methanesulphonamide to form crude fomesafen and (c) purifying the crude fomesafen, characterized in that each of the steps is carried out in a single common solvent, which is preferably a chloroalkane. Preferably the steps are telescoped together so that there is no isolation of the product for any step until fomesafen is obtained

Substituted diphenyl ether herbicides and process for use

This invention relates to substituted diphenyl ethers having selective herbicidal properties and having the formula: STR1 wherein R is a saturated or unsaturated, straight chain or branched aliphatic hydrocarbon radical of from 1 to 18 carbon atoms wherein one or more of the --CH2 -- groups can be replaced with --O--, --S--, --S--S--, --SO--, --SO2 -- or --NR2 -- and said hydrocarbon radical is optionally substituted with halogen, trihalomethyl, cyano, aryl, hydroxy, alkoxy, nitro or cycloalkyl having 3 to 6 carbon atoms; R1 is STR2 R3 is STR3 R2 is hydrogen or a saturated or unsaturated straight or branched chain aliphatic radical having from 1 to 8 carbon atoms, optionally substituted with halogen, hydroxy, alkoxy, cyano or nitro; R4 and R5 are independently a saturated or unsaturated, straight or branched chain aliphatic radical having 1 to 8 carbon atoms optionally substituted with halogen, trihalomethyl, alkoxy or cyano; hydrogen or phenyl optionally substituted with halogen, alkyl, alkoxy, trihalomethyl, nitro or cyano; R6 is a saturated or unsaturated straight chain or branched aliphatic radical containing from 1 to 8 carbon atoms, optionally substituted with halogen, trihalomethyl, cyano, hydroxy, nitro, acetoxy, alkoxy, thioalkoxy or aryl; an aryl radical optionally substituted with halogen, trihalomethyl, hydroxy, cyano, nitro, alkyl or alkoxy; a cyclic 3-6 membered ring alkylene or 5-6 membered ring alkenylene or benzyl optionally substituted with halogen, trihalomethyl, alkyl, hydroxy, alkoxy or cyano; R7 is an alkylene diradical having from 1 to 6 carbon atoms; X and X' are each independently --O--, --S-- or --NR2 -- L, M and N are each independently hydrogen, hydroxy, halogen, trihalomethyl, nitro, cyano, alkyl or alkoxy having from 1 to 4 carbon atoms and STR4 m has a value of from 1 to 6 and n in each instance has a value of from 0 to 1.

Herbicidal 4-trifluoromethyl-3'-carbon-substituted-4'-substituted diphenyl ethers

The herbicidal-4-trifluoromethyl-3'-carbon-substituted-4'-substituted diphenyl ethers comprise a class of compounds that are highly effective herbicides.

Herbicidal 4-trifluoromethyl-3'-nitrogen-substituted-4'-substituted diphenyl ethers

The herbicidal 4-trifluoromethyl-3'-nitrogen-substituted-4'-substituted diphenyl ethers comprise a class of compounds that are highly effective herbicides.

Herbicidal 4-trifluoromethyl-3'-oxygen-substituted-4'-substituted diphenyl ethers

The herbicidal 4-trifluoromethyl-3'-oxygen-substituted-4'-substituted diphenyl ethers comprise a class of compounds that are highly effective herbicides.

Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers

Salts of compounds of the formula STR1 wherein X is a hydrogen atom, a halogen atom, a trihalomethyl group, an alkyl group, or a cyano group, and Y is a hydrogen atom, a halogen atom, or a trihalomethyl group, and compositions containing these salts exhibit herbicidal activity.

Herbicidal 4-trifluoromethyl 4-nitrodiphenyl ethers

Compounds of the formula STR1 wherein X is a cyano group, Y is a hydrogen atom, a halogen atom, or a trihalomethyl group, and Z is a substituted alkoxy group, and compositions containing these compounds exhibit herbicidal activity.

Herbicidal 4-perfluoroacetyl-, 4-perfluoromethylthio-, 4-perfluoromethylsulfinyl-, and 4-perfluoromethylsulfonyl-4'-nitrodiphenyl ethers

The 4-perfluoroacetyl-, 4-perfluoromethylthio-, 4-perfluoromethylsulfinyl-, and 4-perfluoromethylsulfonyl-4'-nitrodiphenyl ethers comprise a class of compounds that are highly effective herbicides.