50594-67-7

Upstream product

• 35852-58-5 2-chloro-4-trifluoromethylphenol 
• 51282-49-6 methyl 5-chloro-2-nitrobenzoate 
• 393-85-1 methyl 5-fluoro-2-nitrobenzoate 
• 50594-66-6 acifluorfen 
• 328-84-7 1,2-dichloro-4-(trifluoromethyl)benzene 
• 63734-62-3 3-(2-chloro-4-(trifluoromethyl)phenoxy)benzoic acid 
• 99-06-9 3-Carboxyphenol 

Downstream Products

• 58105-66-1 methyl 5-(2-chloro-4-trifluoromethylphenoxy)anthranilate 
• 83245-73-2 2-chloro-4-trifluoromethyl-3'-hydroxymethyl-4'-nitrodiphenylether 
• 50594-66-6 acifluorfen 

Relevant academic research and scientific papers

Preparation of trifluoromethylphenyl nitrophenylethers

A process for preparing trifluoromethylphenyl nitro phenylethers which comprises treating a trifluoromethylhalobenzene with a base in a cosolvent system to afford a trifluoromethyl phenolate which may be isolated as its free phenol or reacted with an appropriately substituted halobenzene to afford a diphenylether herbicide or a precursor thereto.

Process for preparing phenoxybenzoic acids

Phenoxybenzoic acids and esters of the formula STR1 wherein R is hydrogen or alkyl and X is hydrogen or chlorine can be prepared by reacting the disalt of 3-hydroxybenzoic acid with a 3-chloro-4-halobenzotrifluoride. These phenoxybenzoic acids and esters can then be selectively nitrated to give the corresponding 2-nitro-5-(substituted)phenoxybenzoic acids and esters. The nitrated esters can also be prepared by first nitrating the corresponding acid and then esterifying with an appropriate alcohol.