637358-02-2Relevant academic research and scientific papers
Synthesis and in vitro evaluation of the anticancer activity of novel fluorinated thiazolo[4,5-d]pyrimidines
Fahmy, Hesham T. Y.,Rostom, Sherif A. F.,Saudi, Manal N.,Zjawiony, Jordan K.,Robins, David J.
, p. 216 - 225 (2003)
The synthesis of several thiazolo[4,5-d]pyrimidines containing a fluorophenyl moiety substituted at different positions and through different bridges is described. Twenty new compounds were prepared and evaluated for their anticancer activity using the US
Synthesis, Structural Characterization and Anticancer Activity of New 5-Trifluoromethyl-2-thioxo-thiazolo[4,5-d] pyrimidine Derivatives
Becan, Lilianna,Bryndal, Iwona,Pyra, Anna,Rembia?kowska, Nina
, (2022/01/24)
Thiazolo[4,5-d]pyrimidine derivatives are considered potential therapeutic agents, partic-ularly in the development of anticancer drugs. In this study, new 7-oxo-(2a-e), 7-chloro-(3a-e) and also three 7-amino-(4a-c) 5-trifluoromethyl-2-thioxo-thiazolo[4,5
Synthesis and antifungal activity of new hybrids thiazolo[4,5-d]pyrimidines with (1H-1,2,4)triazole
Blokhina, Svetlana V.,Doroshenko, Irina A.,Levshin, Igor B.,Ol'khovich, Marina V.,Perlovich, German L.,Sharapova, Angelica V.
, (2021/03/26)
Synthesis and antifungal activity of hybrids of thiazolo[4,5-d]pyrimidines with (1H-1,2,4)triazoles are presented. The solubility and lipophilicity of compounds was assessed and it was discovered that compounds with piperazine linker exhibited significant
