63741-57-1Relevant academic research and scientific papers
HFC-134a as a fluorinated building block: Short syntheses of α- fluoroenones
Bainbridge, J. Marie,Corr, Stuart,Kanai, Masatomi,Percy, Jonathan M.
, p. 971 - 974 (2000)
1,1,1,2-Tetrafluoroethane (HFC-134a) has been transformed into a range of α-fluoroenones via a direct route. Dehydrofluorination/metallation allowed trifluorovinylsilanes to be prepared; these could be converted in situ, or isolated and treated further, with alkyllithium reagents to give difluorovinylsilanes. Fluoride-catalysed addition to aldehydes followed by acidic work-up allowed the isolation of a range of α-fluoroenones in two- or three-pots. (C) 2000 Elsevier Science Ltd.
CETONES α-FLUORO α-ETHYLENIQUES: PREPARATION ET REACTION AVEC LE METHYLURE DE DIMETHYLSULFOXONIUM.
Elkik, Elias,Imbeaux-Oudotte, Michele
, p. 3977 - 3980 (2007/10/02)
Reaction of dimethyl-sulfoxonium methylide with non-halogenated α-ethylenic-ketones is known to lead to cyclopropyl derivatives.With α-fluoro α-ethylenic-ketones this reaction furnishes fluoro-epoxides, by addition of a methylene on carbonyl.
